Literature DB >> 19693312

Atrioventricular block induced by mad-honey intoxication: confirmation of diagnosis by pollen analysis.

Kumral Ergun Cagli1, Omac Tufekcioglu, Nihat Sen, Dursun Aras, Serkan Topaloglu, Nur Basar, Sevil Pehlivan.   

Abstract

An unusual type of food poisoning, mad-honey intoxication, can be observed in the Black Sea region of Turkey and various other parts of the world. It can occur after ingestion of grayanotoxin-contaminated honey produced from the nectar of Rhododendron ponticum and other plant species, chiefly of the Ericaceae and Sapindaceae families. Mad-honey intoxication can result in severe cardiac complications, such as complete atrioventricular block. The diagnosis is generally reached on the basis of the patient's history of honey intake. In this report, we describe the case of a patient who had mad-honey-related complete atrioventricular block; in this instance, the diagnosis was confirmed by a pollen analysis of the suspect honey.

Entities:  

Keywords:  Atropine/therapeutic use; bradycardia/chemically induced; diterpenes/poisoning; food poisoning/complications/diagnosis/therapy; heart block/chemically induced; honey/poisoning; hypotension/chemically induced; ion channels/drug effects; muscarinic antagonists/therapeutic use; plants, toxic/poisoning; pollen analysis; rhododendron; syncope/chemically induced; toxins, biological

Mesh:

Substances:

Year:  2009        PMID: 19693312      PMCID: PMC2720281     

Source DB:  PubMed          Journal:  Tex Heart Inst J        ISSN: 0730-2347


  11 in total

Review 1.  Poisoning by mad honey: a brief review.

Authors:  Ilkay Koca; Ahmet F Koca
Journal:  Food Chem Toxicol       Date:  2007-04-21       Impact factor: 6.023

2.  A case with complete atrioventricular block related to mad honey intoxication.

Authors:  Dursun Dursunoglu; Sukru Gur; Ender Semiz
Journal:  Ann Emerg Med       Date:  2007-10       Impact factor: 5.721

3.  Mad honey poisoning.

Authors:  Abdulkadir Gunduz; Suleyman Turedi; Hukum Uzun; Murat Topbas
Journal:  Am J Emerg Med       Date:  2006-09       Impact factor: 2.469

4.  Cardiac arrhythmias in a patient with grayanotoxin-honey poisoning.

Authors:  H Gossinger; K Hruby; A Haubenstock; A Pohl; S Davogg
Journal:  Vet Hum Toxicol       Date:  1983-10

5.  Hypotension, bradycardia and syncope caused by honey poisoning.

Authors:  Ozcan Yilmaz; Metin Eser; Atilla Sahiner; Levent Altintop; Osman Yesildag
Journal:  Resuscitation       Date:  2006-02-02       Impact factor: 5.262

6.  Mad honey poisoning in man and rat.

Authors:  F Y Onat; B C Yegen; R Lawrence; A Oktay; S Oktay
Journal:  Rev Environ Health       Date:  1991       Impact factor: 3.458

7.  Is the site of action of grayanotoxin the sodium channel gating of squid axon?

Authors:  I Seyama; K Yamaoka; M Yakehiro; Y Yoshioka; K Morihara
Journal:  Jpn J Physiol       Date:  1985

8.  An unusual presentation of mad honey poisoning: acute myocardial infarction.

Authors:  Sinan Akinci; Uğur Arslan; Kamber Karakurt; Atiye Cengel
Journal:  Int J Cardiol       Date:  2007-09-24       Impact factor: 4.164

9.  Mechanism of grayanotoxin III-induced afterpotentials in feline cardiac Purkinje fibers.

Authors:  B S Brown; T Akera; T M Brody
Journal:  Eur J Pharmacol       Date:  1981-11-05       Impact factor: 4.432

10.  Permanent transfemoral pacemaker implantation in a child with Maroteaux Lamy syndrome.

Authors:  Embiya Dilber; Alpay Celiker; Tevfik Karagöz; H Serap Kalkanoğlu
Journal:  Pacing Clin Electrophysiol       Date:  2002-12       Impact factor: 1.976

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  6 in total

1.  Mad-honey sexual activity and acute inferior myocardial infarctions in a married couple.

Authors:  Mikail Yarlioglues; Mahmut Akpek; Idris Ardic; Deniz Elcik; Omer Sahin; Mehmet Gungor Kaya
Journal:  Tex Heart Inst J       Date:  2011

2.  Clinical characteristics and outcomes of patients with grayanotoxin poisoning after the ingestion of mad honey from Nepal.

Authors:  Chang Hwan Sohn; Dong Woo Seo; Seung Mok Ryoo; Jae Ho Lee; Won Young Kim; Kyoung Soo Lim; Bum Jin Oh
Journal:  Intern Emerg Med       Date:  2013-09-12       Impact factor: 3.397

3.  Acute effects of grayanotoxin in rhododendron honey on kidney functions in rats.

Authors:  S Silici; Z Doğan; H Sahin; T Atayoğlu; B Yakan
Journal:  Environ Sci Pollut Res Int       Date:  2015-10-21       Impact factor: 4.223

Review 4.  Grayanotoxin poisoning: 'mad honey disease' and beyond.

Authors:  Suze A Jansen; Iris Kleerekooper; Zonne L M Hofman; Isabelle F P M Kappen; Anna Stary-Weinzinger; Marcel A G van der Heyden
Journal:  Cardiovasc Toxicol       Date:  2012-09       Impact factor: 3.231

5.  Wild honey poisoning: A case report from western Nepal.

Authors:  Anuj Krishna Paudel; Amrit Pokhrel; Suman Gaire; Ananta Hari Paudel; Sujan Poudel; Suman Paudel; Wilson Cueva; George J Michel
Journal:  Clin Case Rep       Date:  2022-03-01

Review 6.  Mad honey: uses, intoxicating/poisoning effects, diagnosis, and treatment.

Authors:  Sana Ullah; Shahid Ullah Khan; Tawfik A Saleh; Shah Fahad
Journal:  RSC Adv       Date:  2018-05-22       Impact factor: 4.036

  6 in total

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