OBJECTIVE: To describe endocrine dysfunction associated with traumatic brain injury in a dog. SUMMARY: A 12-week-old dog presented with traumatic brain injury and did not respond to traditional supportive care. Continued hypothermia, electrolyte derangements, hypotension, and hyposthenuria prompted screening for and detection of several hypothalamic-pituitary disorders including: hypoadrenocorticism, central diabetes insipidus, hypothyroidism, and growth hormone deficiency. Electrolyte abnormalities, urine osmolarity, and blood pressure improved with treatment for the associated disorders. NEW OR UNIQUE INFORMATION PROVIDED: This is the first report of generalized hypothalamic-pituitary dysfunction or panhypopituitarism following traumatic brain injury in a dog.
OBJECTIVE: To describe endocrine dysfunction associated with traumatic brain injury in a dog. SUMMARY: A 12-week-old dog presented with traumatic brain injury and did not respond to traditional supportive care. Continued hypothermia, electrolyte derangements, hypotension, and hyposthenuria prompted screening for and detection of several hypothalamic-pituitary disorders including: hypoadrenocorticism, central diabetes insipidus, hypothyroidism, and growth hormone deficiency. Electrolyte abnormalities, urine osmolarity, and blood pressure improved with treatment for the associated disorders. NEW OR UNIQUE INFORMATION PROVIDED: This is the first report of generalized hypothalamic-pituitary dysfunction or panhypopituitarism following traumatic brain injury in a dog.
Authors: M Judith Radin; Ming-Jiun Yu; Lene Stoedkilde; R Lance Miller; Jason D Hoffert; Jorgen Frokiaer; Trairak Pisitkun; Mark A Knepper Journal: Vet Clin Pathol Date: 2012-11-06 Impact factor: 1.180
Authors: Annemarie M W Y Voorbij; Peter A J Leegwater; Jenny J C W M Buijtels; Sylvie Daminet; Hans S Kooistra Journal: J Vet Intern Med Date: 2015-12-23 Impact factor: 3.333
Authors: Damir Nizamutdinov; Sharon DeMorrow; Matthew McMillin; Jessica Kain; Sanjib Mukherjee; Suzanne Zeitouni; Gabriel Frampton; Paul Clint S Bricker; Jacob Hurst; Lee A Shapiro Journal: Sci Rep Date: 2017-01-20 Impact factor: 4.379