Literature DB >> 1969067

Alpha-ketoglutarate and postoperative muscle catabolism.

J Wernerman1, F Hammarqvist, E Vinnars.   

Abstract

The hypothesis that muscle protein catabolism after trauma is associated with a shortage of alpha-ketoglutarate, rather than glutamine, was tested. Addition of alpha-ketoglutarate to postoperative total parenteral nutrition prevented the decrease in muscle protein synthesis and free glutamine that usually occurs after surgery. alpha-ketoglutarate supplementation may improve recovery after trauma.

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Year:  1990        PMID： 1969067     DOI： 10.1016/0140-6736(90)90811-i

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  12 in total

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