Literature DB >> 196898

Opposite effect of PGE2 on cAMP levels in human adrenal medulla and pheochromocytoma.

P Boonyaviroj, Y Gutman.   

Abstract

PGE2 (10(-7) M) caused increased cAMP accumlation in 5 pheochromocytomas, while in 3 human adrenal medullae PGE2 caused a significant decrease of cAMP level on incubating slices in vitro. This finding is discussed in relation to the opposite effect of PGE2 on catecholamine release from human medulla and pheochromocytoma slices in vitro.

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Year:  1977        PMID: 196898     DOI: 10.1007/bf01946002

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  5 in total

1.  The effect of PGE-1 on cyclic AMP and ion movements in turkey erythrocytes.

Authors:  J Shaw; W Gibson; S Jessup; P Ramwell
Journal:  Ann N Y Acad Sci       Date:  1971-04-30       Impact factor: 5.691

2.  Alpha-adrenergic stimulants, prostaglandins and catecholamine release from the adrenal gland in vitro.

Authors:  P Boonyaviroj; Y Gutman
Journal:  Prostaglandins       Date:  1975-07

3.  PGE2: opposite effect on catecholamine release from phaeochromocytoma and adrenal medulla.

Authors:  Y Gutman; P Boonyaviroj
Journal:  Prostaglandins       Date:  1976-10

4.  Inhibition by PGE2 and by phenylephrine of catecholamine release from human adrenal in vitro.

Authors:  P Boonyaviroj; Y Gutman
Journal:  Eur J Pharmacol       Date:  1977-01-07       Impact factor: 4.432

5.  Stimulation of release of adrenal catecholamine by adenosine 3':5'-cyclic monophosphate and theophylline in the absence of extracellular Ca 2+ .

Authors:  M J Peach
Journal:  Proc Natl Acad Sci U S A       Date:  1972-04       Impact factor: 11.205

  5 in total

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