Literature DB >> 19689756

Hyperthermia exacerbates ischaemic brain injury.

C X Wang1, A Stroink, J M Casto, K Kattner.   

Abstract

Hyperthermia frequently occurs in stroke patients. Hyperthermia negatively correlates with clinical outcome and adversely effects treatment regiments otherwise successful under normothermic conditions. Preclinical studies also demonstrate that hyperthermia converts salvageable penumbra to ischaemic infarct. The present article reviews the knowledge accumulated from both clinical and preclinical studies about hyperthermia and ischaemic brain injury, examines current treatment strategies and discusses future research directions.

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Year:  2009        PMID： 19689756     DOI： 10.1111/j.1747-4949.2009.00317.x

Source DB:  PubMed          Journal:  Int J Stroke        ISSN： 1747-4930            Impact factor:   5.266


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