Literature DB >> 19689406

ABC transporters as potential targets for modulation of drug resistance.

L Gatti1, G L Beretta, G Cossa, F Zunino, P Perego.   

Abstract

ATP binding cassette transporters are implicated in multidrug resistant phenotypes of tumor cells and may be cancer stem cell markers. Inhibitors of drug efflux pumps represent an emerging group of potentially useful agents for the improvement of antitumor therapy. Here we provide an overview of drug transporter functions and modulation.

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Year:  2009        PMID： 19689406     DOI： 10.2174/138955709788922656

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  16 in total

1.  The ABC of glycosylation.

Authors:  Paola Perego; Laura Gatti; Giovanni L Beretta
Journal:  Nat Rev Cancer       Date:  2010-06-10       Impact factor: 60.716

2.  Anticancer effects of the nitric oxide-modified saquinavir derivative saquinavir-NO against multidrug-resistant cancer cells.

Authors:  Florian Rothweiler; Martin Michaelis; Peter Brauer; Jürgen Otte; Kristoffer Weber; Boris Fehse; Hans Wilhelm Doerr; Michael Wiese; Jörg Kreuter; Yousef Al-Abed; Ferdinando Nicoletti; Jindrich Cinatl
Journal:  Neoplasia       Date:  2010-12       Impact factor: 5.715

3.  Influence of efflux pump inhibitors on the multidrug resistance of Helicobacter pylori.

Authors:  Zhan Zhang; Zhi-Qiang Liu; Peng-Yuan Zheng; Fu-Ai Tang; Ping-Chang Yang
Journal:  World J Gastroenterol       Date:  2010-03-14       Impact factor: 5.742

4.  Targeting the mechanisms of resistance to chemotherapy and radiotherapy with the cancer stem cell hypothesis.

Authors:  Ryan Morrison; Stephen M Schleicher; Yunguang Sun; Kenneth J Niermann; Sungjune Kim; Daniel E Spratt; Christine H Chung; Bo Lu
Journal:  J Oncol       Date:  2010-10-12       Impact factor: 4.375

5.  Clinicopathological impact of ABCC1/MRP1 and ABCC4/MRP4 in epithelial ovarian carcinoma.

Authors:  Marina Bagnoli; Giovanni L Beretta; Laura Gatti; Silvana Pilotti; Paola Alberti; Eva Tarantino; Mattia Barbareschi; Silvana Canevari; Delia Mezzanzanica; Paola Perego
Journal:  Biomed Res Int       Date:  2013-08-19       Impact factor: 3.411

6.  Multidrug Resistance-Associated Protein 2 (MRP2) Mediated Transport of Oxaliplatin-Derived Platinum in Membrane Vesicles.

Authors:  Khine Myint; Yan Li; James Paxton; Mark McKeage
Journal:  PLoS One       Date:  2015-07-01       Impact factor: 3.240

7.  The role of copper transporter ATP7A in platinum-resistance of esophageal squamous cell cancer (ESCC).

Authors:  Zhuang-Hua Li; Rongjie Zheng; Jing-Tang Chen; Jun Jia; Miaozhen Qiu
Journal:  J Cancer       Date:  2016-10-23       Impact factor: 4.207

8.  Downregulation of HIF-2α Reverse the Chemotherapy Resistance of Lung Adenocarcinoma A549 Cells to Cisplatin.

Authors:  Zhao-Jia Gao; Wei-Dong Yuan; Jun-Qiang Yuan; Kai Yuan; Yong Wang
Journal:  Med Sci Monit       Date:  2018-02-22

9.  Curcumin Improves the Tumoricidal Effect of Mitomycin C by Suppressing ABCG2 Expression in Stem Cell-Like Breast Cancer Cells.

Authors:  Qianmei Zhou; Meina Ye; Yiyu Lu; Hui Zhang; Qilong Chen; Shuang Huang; Shibing Su
Journal:  PLoS One       Date:  2015-08-25       Impact factor: 3.240

10.  Dacomitinib potentiates the efficacy of conventional chemotherapeutic agents via inhibiting the drug efflux function of ABCG2 in vitro and in vivo.

Authors:  Xiaoran Guo; Kenneth K W To; Zhen Chen; Xiaokun Wang; Jianye Zhang; Min Luo; Fang Wang; Shirong Yan; Liwu Fu
Journal:  J Exp Clin Cancer Res       Date:  2018-02-20
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