Literature DB >> 196885

Isethionate may not be an inert substitute for extracellular chloride in the central nervous system.

N Bernardi, J A Assumpção, N Davidson, C G Dacke.   

Abstract

Replacement of extracellular chloride with isethionate or methylsulphate causes an increased efflux of 1-[14C]-GABA from the in vivo superfused rat cuneate nucleus. This raises the question of the suitability of these anions as inert substitutes for chloride in studies on the ionic dependency of membrane phenomena in the central nervous system.

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Year:  1977        PMID: 196885     DOI: 10.1007/bf01951278

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  6 in total

1.  A STUDY OF SPONTANEOUS MINIATURE POTENTIALS IN SPINAL MOTONEURONES.

Authors:  B KATZ; R MILEDI
Journal:  J Physiol       Date:  1963-09       Impact factor: 5.182

2.  A superfusion technique for isotope efflux studies and concurrent electrophysiological investigation in the rat cuneate nucleus [proceedings].

Authors:  J A Assumçrao; N Bernardi; C G Dacke; N Davidson
Journal:  J Physiol       Date:  1976-12       Impact factor: 5.182

3.  Concerning the ionic basis of presynaptic inhibition.

Authors:  N Davidson; H K Simpson
Journal:  Experientia       Date:  1976-03-15

4.  Primary afferent neurones: the ionic mechanism of GABA-mediated depolarization.

Authors:  S Nishi; S Minota; A G Karczmar
Journal:  Neuropharmacology       Date:  1974-03       Impact factor: 5.250

5.  The pharmacology and ionic dependency of amino acid responses in the frog spinal cord.

Authors:  J L Barker; R A Nicoll
Journal:  J Physiol       Date:  1973-01       Impact factor: 5.182

6.  Amino acids and presynaptic inhibition in the rat cuneate nucleus.

Authors:  N Davidson; C A Southwick
Journal:  J Physiol       Date:  1971-12       Impact factor: 5.182

  6 in total

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