Literature DB >> 19688131

A case of medullary thyroid carcinoma in which the skin metastasis was concurrently present and response occurred to chemotherapy.

Won Je Choi1, Yun Young Lee, Soyon Kim, Yun Kwon Kim, Eun Sil Kim, Seung O Seo, Jae Hyun Jo, Seung Min Lee, Hyo Jin Lee.   

Abstract

Medullary thyroid carcinoma accounts for 3% of all thyroid gland malignancies. It commonly metastasizes to liver, lung, and bone. It rarely metastasizes to skin, and only a few such cases have been documented. Cutaneous metastasis suggests a poor prognosis, with a mean survival of 7.5-19 months. The most effective treatment for skin metastasis is complete surgical removal of all local and regional lesions. The response to systemic chemotherapy is typically poor. We report a case of medullary thyroid carcinoma with cutaneous metastases, which responded to chemotherapy.

Entities:  

Keywords:  Chemotherapy; Cutaneous metastases; Medullary thyroid carcinoma

Year:  2008        PMID: 19688131      PMCID: PMC2697479          DOI: 10.4143/crt.2008.40.4.202

Source DB:  PubMed          Journal:  Cancer Res Treat        ISSN: 1598-2998            Impact factor:   4.679


  7 in total

1.  Epidermotropic metastatic malignant melanoma with a pedunculated appearance.

Authors:  H Hayashi; T Kawashima; K Hosokawa; T Kiyohara; H Kobayashi; A Ohkawara; H Shimizu
Journal:  Clin Exp Dermatol       Date:  2003-11       Impact factor: 3.470

2.  Metastatic tumors of the skin.

Authors:  M H Brownstein; E B Helwig
Journal:  Cancer       Date:  1972-05       Impact factor: 6.860

3.  Thyroid carcinoma--biologic behavior and mortality. Postmortem findings in 42 cases, including 27 in which the disease was fatal.

Authors:  M L Ibanez; W O Russell; J Albores-Saavedra; P Lampertico; E C White; R L Clark
Journal:  Cancer       Date:  1966-08       Impact factor: 6.860

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Authors:  U Runne; G Mödder
Journal:  Dtsch Med Wochenschr       Date:  1976-12-10       Impact factor: 0.628

Review 5.  Thyroid carcinoma metastatic to the skin: a cutaneous manifestation of a widely disseminated malignancy.

Authors:  P R Dahl; D G Brodland; J R Goellner; I D Hay
Journal:  J Am Acad Dermatol       Date:  1997-04       Impact factor: 11.527

6.  Medullary carcinoma of the thyroid metastatic to the skin: report of two cases.

Authors:  N G Ordóñez; N A Samaan
Journal:  J Cutan Pathol       Date:  1987-08       Impact factor: 1.587

Review 7.  Cutaneous manifestations of thyroid cancer: a report of four cases and review of the literature.

Authors:  S Alwaheeb; D Ghazarian; S L Boerner; S L Asa
Journal:  J Clin Pathol       Date:  2004-04       Impact factor: 3.411

  7 in total
  1 in total

1.  Cutaneous metastasis of medullary carcinoma thyroid masquerading as subcutaneous nodules anterior chest and mandibular region.

Authors:  Rahul Mannan; Jasmine Kaur; Jasleen Kaur; Sanjay Piplani; Harjot Kaur; Harleen Kaur
Journal:  Case Rep Dermatol Med       Date:  2014-11-11
  1 in total

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