Literature DB >> 19687244

Fluoroquinolone resistance in Mycobacterium tuberculosis and mutations in gyrA and gyrB.

Andrea Von Groll1, Anandi Martin, Pontus Jureen, Sven Hoffner, Peter Vandamme, Françoise Portaels, Juan Carlos Palomino, Pedro Almeida da Silva.   

Abstract

This study evaluated cross-resistance of Mycobacterium tuberculosis strains to ofloxacin, moxifloxacin, and gatifloxacin and investigated the presence of mutations in gyrA and gyrB. Fluoroquinolone susceptibilities were determined for 41 M. tuberculosis strains by the proportion method on 7H11, and MICs were determined by the resazurin microtiter assay. Forty strains shared the same resistance results for the three fluoroquinolones. However, one strain, with an Asn-533 --> Thr mutation in gyrB, was susceptible to ofloxacin but resistant to moxifloxacin and gatifloxacin.

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Year:  2009        PMID： 19687244      PMCID： PMC2764174          DOI： 10.1128/AAC.00287-09

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  24 in total

1.  Genotypic characterization of drug-resistant Mycobacterium tuberculosis isolates from Peru.

Authors:  P Escalante; S Ramaswamy; H Sanabria; H Soini; X Pan; O Valiente-Castillo; J M Musser
Journal:  Tuber Lung Dis       Date:  1998

2.  Characterization of pyrazinamide and ofloxacin resistance among drug resistant Mycobacterium tuberculosis isolates from Singapore.

Authors:  Ann S G Lee; Lynn L H Tang; Irene H K Lim; Sin Yew Wong
Journal:  Int J Infect Dis       Date:  2002-03       Impact factor: 3.623

3.  Fluoroquinolone resistance associated with specific gyrase mutations in clinical isolates of multidrug-resistant Mycobacterium tuberculosis.

Authors:  C Xu; B N Kreiswirth; S Sreevatsan; J M Musser; K Drlica
Journal:  J Infect Dis       Date:  1996-11       Impact factor: 5.226

4.  In vitro and in vivo activities of gatifloxacin against Mycobacterium tuberculosis.

Authors:  Enrique J Alvirez-Freites; Janna L Carter; Michael H Cynamon
Journal:  Antimicrob Agents Chemother       Date:  2002-04       Impact factor: 5.191

5.  Cloning and nucleotide sequence of Mycobacterium tuberculosis gyrA and gyrB genes and detection of quinolone resistance mutations.

Authors:  H E Takiff; L Salazar; C Guerrero; W Philipp; W M Huang; B Kreiswirth; S T Cole; W R Jacobs; A Telenti
Journal:  Antimicrob Agents Chemother       Date:  1994-04       Impact factor: 5.191

6.  Rv2686c-Rv2687c-Rv2688c, an ABC fluoroquinolone efflux pump in Mycobacterium tuberculosis.

Authors:  Maria Rosalia Pasca; Paola Guglierame; Fabio Arcesi; Marco Bellinzoni; Edda De Rossi; Giovanna Riccardi
Journal:  Antimicrob Agents Chemother       Date:  2004-08       Impact factor: 5.191

7.  Correlation between quinolone susceptibility patterns and sequences in the A and B subunits of DNA gyrase in mycobacteria.

Authors:  I Guillemin; V Jarlier; E Cambau
Journal:  Antimicrob Agents Chemother       Date:  1998-08       Impact factor: 5.191

8.  Efflux pump of the proton antiporter family confers low-level fluoroquinolone resistance in Mycobacterium smegmatis.

Authors:  H E Takiff; M Cimino; M C Musso; T Weisbrod; R Martinez; M B Delgado; L Salazar; B R Bloom; W R Jacobs
Journal:  Proc Natl Acad Sci U S A       Date:  1996-01-09       Impact factor: 11.205

9.  Detection of mutations in Mycobacterium tuberculosis genome determining resistance to fluoroquinolones by hybridization on biological microchips.

Authors:  O V Antonova; D A Gryadunov; S A Lapa; A V Kuz'min; E E Larionova; T G Smirnova; E Y Nosova; O I Skotnikova; L N Chernousova; A M Moroz; A S Zasedatelev; V M Mikhailovich
Journal:  Bull Exp Biol Med       Date:  2008-01       Impact factor: 0.804

10.  Characterization of fluoroquinolone-resistant mutant strains of Mycobacterium tuberculosis selected in the laboratory and isolated from patients.

Authors:  G J Alangaden; E K Manavathu; S B Vakulenko; N M Zvonok; S A Lerner
Journal:  Antimicrob Agents Chemother       Date:  1995-08       Impact factor: 5.191
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  65 in total

Review 1.  A systematic review of gyrase mutations associated with fluoroquinolone-resistant Mycobacterium tuberculosis and a proposed gyrase numbering system.

Authors:  Fernanda Maruri; Timothy R Sterling; Anne W Kaiga; Amondrea Blackman; Yuri F van der Heijden; Claudine Mayer; Emmanuelle Cambau; Alexandra Aubry
Journal:  J Antimicrob Chemother       Date:  2012-01-25       Impact factor: 5.790

2.  Performance of the New Version (v2.0) of the GenoType MTBDRsl Test for Detection of Resistance to Second-Line Drugs in Multidrug-Resistant Mycobacterium tuberculosis Complex Strains.

Authors:  Florence Brossier; David Guindo; Anne Pham; Florence Reibel; Wladimir Sougakoff; Nicolas Veziris; Alexandra Aubry
Journal:  J Clin Microbiol       Date:  2016-04-06       Impact factor: 5.948

3.  Evaluation of two molecular assays for rapid detection of mycobacterium tuberculosis resistance to fluoroquinolones in high-tuberculosis and -multidrug-resistance Settings.

Authors:  I Kontsevaya; S Mironova; V Nikolayevskyy; Y Balabanova; S Mitchell; F Drobniewski
Journal:  J Clin Microbiol       Date:  2011-06-01       Impact factor: 5.948

Review 4.  Current prospects for the fluoroquinolones as first-line tuberculosis therapy.

Authors:  Howard Takiff; Elba Guerrero
Journal:  Antimicrob Agents Chemother       Date:  2011-08-29       Impact factor: 5.191

Review 5.  Drug-resistance in Mycobacterium tuberculosis: where we stand.

Authors:  Amanda Mabhula; Vinayak Singh
Journal:  Medchemcomm       Date:  2019-06-11       Impact factor: 3.597

6.  Mycobacterium tuberculosis gyrase inhibitors as a new class of antitubercular drugs.

Authors:  Delia Blanco; Esther Perez-Herran; Mónica Cacho; Lluís Ballell; Julia Castro; Rubén González Del Río; José Luis Lavandera; Modesto J Remuiñán; Cindy Richards; Joaquin Rullas; María Jesús Vázquez-Muñiz; Ermias Woldu; María Cleofé Zapatero-González; Iñigo Angulo-Barturen; Alfonso Mendoza; David Barros
Journal:  Antimicrob Agents Chemother       Date:  2015-01-12       Impact factor: 5.191

7.  De Novo Emergence of Genetically Resistant Mutants of Mycobacterium tuberculosis from the Persistence Phase Cells Formed against Antituberculosis Drugs In Vitro.

Authors:  Jees Sebastian; Sharmada Swaminath; Rashmi Ravindran Nair; Kishor Jakkala; Atul Pradhan; Parthasarathi Ajitkumar
Journal:  Antimicrob Agents Chemother       Date:  2017-01-24       Impact factor: 5.191

8.  DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis.

Authors:  Alix Pantel; Stéphanie Petrella; Stéphanie Matrat; Florence Brossier; Sylvaine Bastian; Delphine Reitter; Vincent Jarlier; Claudine Mayer; Alexandra Aubry
Journal:  Antimicrob Agents Chemother       Date:  2011-07-18       Impact factor: 5.191

Review 9.  Cure of tuberculosis using nanotechnology: An overview.

Authors:  Rout George Kerry; Sushanto Gouda; Bikram Sil; Gitishree Das; Han-Seung Shin; Gajanan Ghodake; Jayanta Kumar Patra
Journal:  J Microbiol       Date:  2018-05-02       Impact factor: 3.422

10.  Triplex real-time PCR melting curve analysis for detecting Mycobacterium tuberculosis mutations associated with resistance to second-line drugs in a single reaction.

Authors:  Qingyun Liu; Tao Luo; Jing Li; Jian Mei; Qian Gao
Journal:  J Antimicrob Chemother       Date:  2013-01-03       Impact factor: 5.790
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