OBJECTIVE: Population-based surveys have confirmed that psychotic-like experiences are prevalent in the community. However, it is unclear if these experiences are associated with common mental disorders. The aim of this study was to examine the prevalence of psychotic-like experiences in those with affective and anxiety disorders. METHODS: Subjects were drawn from the Mater-University of Queensland Study of Pregnancy. Delusion-like experiences were assessed with the Peters Delusional Inventory (PDI). The Composite International Diagnostic Interview (CIDI) was used to identify individuals with Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) lifetime diagnoses of major depression, anxiety disorder, substance use/dependence, and psychotic disorders. The influence of affective and anxiety disorders on PDI and CIDI psychosis-related items' scores were assessed with logistic regression, with adjustments for age, sex, and the presence of the other comorbid psychiatric diagnoses. RESULTS: Having either a lifetime diagnosis of major depressive disorder or an anxiety disorder was associated with significantly higher PDI total scores (highest vs lowest quartile adjusted odds ratios [ORs] and 95% confidence intervals [CIs] = 4.43, 3.09-6.36; 3.08, 2.26-4.20, respectively). The odds of endorsing any CIDI hallucination or delusion item was increased in those with a major depressive or anxiety disorder. The presence of current anxiety disorder symptoms was significantly associated with PDI score (OR = 5.81, 95% CI = 3.68-9.16). CONCLUSION: While psychotic-like experiences are usually associated with psychotic disorders, individuals with depression and anxiety are also more likely to report these symptoms compared with well individuals. Psychotic-like experiences are associated with a range of common mental disorders.
OBJECTIVE: Population-based surveys have confirmed that psychotic-like experiences are prevalent in the community. However, it is unclear if these experiences are associated with common mental disorders. The aim of this study was to examine the prevalence of psychotic-like experiences in those with affective and anxiety disorders. METHODS: Subjects were drawn from the Mater-University of Queensland Study of Pregnancy. Delusion-like experiences were assessed with the Peters Delusional Inventory (PDI). The Composite International Diagnostic Interview (CIDI) was used to identify individuals with Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) lifetime diagnoses of major depression, anxiety disorder, substance use/dependence, and psychotic disorders. The influence of affective and anxiety disorders on PDI and CIDI psychosis-related items' scores were assessed with logistic regression, with adjustments for age, sex, and the presence of the other comorbid psychiatric diagnoses. RESULTS: Having either a lifetime diagnosis of major depressive disorder or an anxiety disorder was associated with significantly higher PDI total scores (highest vs lowest quartile adjusted odds ratios [ORs] and 95% confidence intervals [CIs] = 4.43, 3.09-6.36; 3.08, 2.26-4.20, respectively). The odds of endorsing any CIDI hallucination or delusion item was increased in those with a major depressive or anxiety disorder. The presence of current anxiety disorder symptoms was significantly associated with PDI score (OR = 5.81, 95% CI = 3.68-9.16). CONCLUSION: While psychotic-like experiences are usually associated with psychotic disorders, individuals with depression and anxiety are also more likely to report these symptoms compared with well individuals. Psychotic-like experiences are associated with a range of common mental disorders.
Authors: Louise C Johns; Mary Cannon; Nicola Singleton; Robin M Murray; Michael Farrell; Traolach Brugha; Paul Bebbington; Rachel Jenkins; Howard Meltzer Journal: Br J Psychiatry Date: 2004-10 Impact factor: 9.319
Authors: Y van der Steen; I Myin-Germeys; M van Nierop; M Ten Have; R de Graaf; S van Dorsselaer; J van Os; R van Winkel Journal: Epidemiol Psychiatr Sci Date: 2018-04-16 Impact factor: 6.892
Authors: John J McGrath; Sukanta Saha; Ali Al-Hamzawi; Laura Andrade; Corina Benjet; Evelyn J Bromet; Mark Oakley Browne; Jose M Caldas de Almeida; Wai Tat Chiu; Koen Demyttenaere; John Fayyad; Silvia Florescu; Giovanni de Girolamo; Oye Gureje; Josep Maria Haro; Margreet Ten Have; Chiyi Hu; Viviane Kovess-Masfety; Carmen C W Lim; Fernando Navarro-Mateu; Nancy Sampson; José Posada-Villa; Kenneth S Kendler; Ronald C Kessler Journal: Am J Psychiatry Date: 2016-03-17 Impact factor: 18.112