Literature DB >> 19687059

Current and future aberration correctors for the improvement of resolution in electron microscopy.

M Haider1, P Hartel, H Müller, S Uhlemann, J Zach.   

Abstract

The achievable resolution of a modern transmission electron microscope (TEM) is mainly limited by the inherent aberrations of the objective lens. Hence, one major goal over the past decade has been the development of aberration correctors to compensate the spherical aberration. Such a correction system is now available and it is possible to improve the resolution with this corrector. When high resolution in a TEM is required, one important parameter, the field of view, also has to be considered. In addition, especially for the large cameras now available, the compensation of off-axial aberrations is also an important task. A correction system to compensate the spherical aberration and the off-axial coma is under development. The next step to follow towards ultra-high resolution will be a correction system to compensate the chromatic aberration. With such a correction system, a new area will be opened for applications for which the chromatic aberration defines the achievable resolution, even if the spherical aberration is corrected. This is the case, for example, for low-voltage electron microscopy (EM) for the investigation of beam-sensitive materials, for dynamic EM or for in-situ EM.

Entities:  

Year:  2009        PMID: 19687059     DOI: 10.1098/rsta.2009.0121

Source DB:  PubMed          Journal:  Philos Trans A Math Phys Eng Sci        ISSN: 1364-503X            Impact factor:   4.226


  4 in total

Review 1.  Electron microscopy of specimens in liquid.

Authors:  Niels de Jonge; Frances M Ross
Journal:  Nat Nanotechnol       Date:  2011-10-23       Impact factor: 39.213

2.  Sub-2 Angstrom resolution structure determination using single-particle cryo-EM at 200 keV.

Authors:  Mengyu Wu; Gabriel C Lander; Mark A Herzik
Journal:  J Struct Biol X       Date:  2020-02-28

Review 3.  Coherent Diffraction Imaging in Transmission Electron Microscopy for Atomic Resolution Quantitative Studies of the Matter.

Authors:  Elvio Carlino; Francesco Scattarella; Liberato De Caro; Cinzia Giannini; Dritan Siliqi; Alessandro Colombo; Davide Emilio Galli
Journal:  Materials (Basel)       Date:  2018-11-19       Impact factor: 3.623

4.  Single-particle cryo-EM at atomic resolution.

Authors:  Takanori Nakane; Abhay Kotecha; Andrija Sente; Greg McMullan; Simonas Masiulis; Patricia M G E Brown; Ioana T Grigoras; Lina Malinauskaite; Tomas Malinauskas; Jonas Miehling; Tomasz Uchański; Lingbo Yu; Dimple Karia; Evgeniya V Pechnikova; Erwin de Jong; Jeroen Keizer; Maarten Bischoff; Jamie McCormack; Peter Tiemeijer; Steven W Hardwick; Dimitri Y Chirgadze; Garib Murshudov; A Radu Aricescu; Sjors H W Scheres
Journal:  Nature       Date:  2020-10-21       Impact factor: 69.504

  4 in total

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