Literature DB >> 19686699

Toll-like receptors and innate immunity.

Himanshu Kumar1, Taro Kawai, Shizuo Akira.   

Abstract

Toll-like receptors (TLRs) are evolutionarily conserved innate receptors expressed in various immune and non-immune cells of the mammalian host. TLRs play a crucial role in defending against pathogenic microbial infection through the induction of inflammatory cytokines and type I interferons. Furthermore, TLRs also play roles in shaping pathogen-specific humoral and cellular adaptive immune responses. In this review, we describe the recent advances in pathogen recognition by TLRs and TLR signaling.

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Year:  2009        PMID： 19686699     DOI： 10.1016/j.bbrc.2009.08.062

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  391 in total

1.  Ehrlichia chaffeensis induces monocyte inflammatory responses through MyD88, ERK, and NF-κB but not through TRIF, interleukin-1 receptor 1 (IL-1R1)/IL-18R1, or toll-like receptors.

Authors:  Koshiro Miura; Junji Matsuo; M Akhlakur Rahman; Yumi Kumagai; Xin Li; Yasuko Rikihisa
Journal:  Infect Immun       Date:  2011-09-19       Impact factor: 3.441

2.  Klebsiella pneumoniae outer membrane protein A is required to prevent the activation of airway epithelial cells.

Authors:  Catalina March; David Moranta; Verónica Regueiro; Enrique Llobet; Anna Tomás; Junkal Garmendia; José A Bengoechea
Journal:  J Biol Chem       Date:  2011-01-28       Impact factor: 5.157

Review 3.  Hematopoiesis sculpted by pathogens: Toll-like receptors and inflammatory mediators directly activate stem cells.

Authors:  Julie R Boiko; Lisa Borghesi
Journal:  Cytokine       Date:  2011-11-12       Impact factor: 3.861

Review 4.  Messenger functions of the bacterial cell wall-derived muropeptides.

Authors:  Marc A Boudreau; Jed F Fisher; Shahriar Mobashery
Journal:  Biochemistry       Date:  2012-03-27       Impact factor: 3.162

Review 5.  A bacterial siren song: intimate interactions between Neisseria and neutrophils.

Authors:  Alison K Criss; H Steven Seifert
Journal:  Nat Rev Microbiol       Date:  2012-01-31       Impact factor: 60.633

6.  Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering.

Authors:  Sang-Chul Lee; Keunwan Park; Jieun Han; Joong-jae Lee; Hyun Jung Kim; Seungpyo Hong; Woosung Heu; Yu Jung Kim; Jae-Seok Ha; Seung-Goo Lee; Hae-Kap Cheong; Young Ho Jeon; Dongsup Kim; Hak-Sung Kim
Journal:  Proc Natl Acad Sci U S A       Date:  2012-02-10       Impact factor: 11.205

7.  Different patterns of Toll-like receptor 2 polymorphisms in populations of various ethnic and geographic origins.

Authors:  M Ioana; B Ferwerda; T S Plantinga; M Stappers; M Oosting; M McCall; A Cimpoeru; F Burada; N Panduru; R Sauerwein; O Doumbo; J W M van der Meer; R van Crevel; L A B Joosten; M G Netea
Journal:  Infect Immun       Date:  2012-02-21       Impact factor: 3.441

Review 8.  Disc in flames: Roles of TNF-α and IL-1β in intervertebral disc degeneration.

Authors:  Z I Johnson; Z R Schoepflin; H Choi; I M Shapiro; M V Risbud
Journal:  Eur Cell Mater       Date:  2015-09-21       Impact factor: 3.942

Review 9.  The role of dendritic cells in driving genital tract inflammation and HIV transmission risk: are there opportunities to intervene?

Authors:  Muki S Shey; Nigel J Garrett; Lyle R McKinnon; Jo-Ann S Passmore
Journal:  Innate Immun       Date:  2013-11-26       Impact factor: 2.680

10.  A purified capsular polysaccharide markedly inhibits inflammatory response during endotoxic shock.

Authors:  M Piccioni; C Monari; S Kenno; E Pericolini; E Gabrielli; D Pietrella; S Perito; F Bistoni; T R Kozel; A Vecchiarelli
Journal:  Infect Immun       Date:  2012-10-22       Impact factor: 3.441
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