| Literature DB >> 1968656 |
R L Adams1, M Bryans, A Rinaldi, A Smart, H M Yesufu.
Abstract
DNA methylases from mouse and pea have been purified and characterized. Both are high molecular mass enzymes that show greater activity with hemimethylated than unmethylated substrate DNA. Both methylate cytosines in CpG preferentially, but not exclusively and show similar kinetics of methylation, which makes it difficult to saturate all possible sites on the DNA, but procedures are described that circumvent this problem.Entities:
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Year: 1990 PMID： 1968656 DOI： 10.1098/rstb.1990.0003
Source DB: PubMed Journal: Philos Trans R Soc Lond B Biol Sci ISSN： 0962-8436 Impact factor: 6.237