Literature DB >> 19685830

[Case report of mucormycosis in a patient with secondary methimazole-induced agranulocytosis].

Claudia Ramírez1, Alex Francisco Hernández, Verna Méndez, Silvia Trejo, Roxana Contreras, Ana Laura Espinosa de los Monteros, Luz Maria Gómez, Moisés Mercado.   

Abstract

Agranulocytosis is a rare side effect of antithyroid drugs, it occurs in less than 0.5% of patients, usually during the first few months of treatment. It is considered to be the most serious adverse effect of these medications since it may be complicated by serious, life-threatening infections. Mucormycosis is a severe mycotic infection that usually develops in immunocompromised hosts, such aspatients with diabetes mellitus, hematologic malignancies or immunosuppressive therapy. The association of mucormycosis with methimazole-induced agranulocytosis has not been previously described. The objective of this case presentation is to analyze the case ofa woman with diffuse toxic goiter and methimazole-induced agranulocytosis who developed rhino-palatal mucormycosis.

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Year:  2009        PMID: 19685830

Source DB:  PubMed          Journal:  Gac Med Mex        ISSN: 0016-3813            Impact factor:   0.302


  2 in total

1.  Sepsis mimicking thyroid storm in a patient with methimazole-induced agranulocytosis.

Authors:  Samuel G Rayner; Faegheh Hosseini; Adeyinka A Adedipe
Journal:  BMJ Case Rep       Date:  2013-07-16

2.  Epidemiology of Invasive Fungal Infections in Latin America.

Authors:  Jose Sifuentes-Osornio; Dora E Corzo-León; L Alfredo Ponce-de-León
Journal:  Curr Fungal Infect Rep       Date:  2012-01-05
  2 in total

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