Literature DB >> 19685291

Neural circuitry associated with risk for alcohol use disorders.

Kevin D Tessner1, Shirley Y Hill.   

Abstract

The core features of risk for alcohol use disorders (AUD), including behavioral disinhibition, affective dysregulation, and executive dysfunction, map onto distinct neural circuits that have been found to be abnormal in the offspring of alcohol dependent individuals. Components of the cerebellothalamocortical system and the extended limbic network may provide the underpinnings for the behavioral and emotional dysfunction observed in individuals at heightened risk for AUD. In addition, abnormalities in these structures appear to be altered in individuals with the predisposition for other psychiatric conditions that may share a similar genetic diathesis. This review proposes several neurobehavioral mechanisms of genetic vulnerability that may account for phenotypic characteristics in individuals at risk for AUD.

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Year:  2009        PMID： 19685291      PMCID： PMC3580188          DOI： 10.1007/s11065-009-9111-4

Source DB:  PubMed          Journal:  Neuropsychol Rev        ISSN： 1040-7308            Impact factor:   7.444


  266 in total

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3.  Cerebellar development and clinical outcome in attention deficit hyperactivity disorder.

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Review 5.  Advances in understanding ventromedial prefrontal function: the accountant joins the executive.

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Journal:  Neurology       Date:  2007-03-27       Impact factor: 9.910

6.  Reduced amygdala activation in young adults at high risk of alcoholism: studies from the Oklahoma family health patterns project.

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8.  Lifetime prevalence, correlates, and persistence of oppositional defiant disorder: results from the National Comorbidity Survey Replication.

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Review 9.  Genetic influences on human brain structure: a review of brain imaging studies in twins.

Authors:  Jiska S Peper; Rachel M Brouwer; Dorret I Boomsma; René S Kahn; Hilleke E Hulshoff Pol
Journal:  Hum Brain Mapp       Date:  2007-06       Impact factor: 5.038

10.  Response of the HPA-axis to alcohol and stress as a function of alcohol dependence and family history of alcoholism.

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Journal:  Psychoneuroendocrinology       Date:  2007-03-08       Impact factor: 4.905
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  41 in total

1.  Chronic cigarette smoking in alcohol dependence: associations with cortical thickness and N-acetylaspartate levels in the extended brain reward system.

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Review 4.  The relationship of appetitive, reproductive and posterior pituitary hormones to alcoholism and craving in humans.

Authors:  George A Kenna; Robert M Swift; Thomas Hillemacher; Lorenzo Leggio
Journal:  Neuropsychol Rev       Date:  2012-07-07       Impact factor: 7.444

5.  Altered fronto-cerebellar connectivity in alcohol-naïve youth with a family history of alcoholism.

Authors:  Megan M Herting; Damien Fair; Bonnie J Nagel
Journal:  Neuroimage       Date:  2010-10-21       Impact factor: 6.556

Review 6.  The cerebellum and addiction: insights gained from neuroimaging research.

Authors:  Eric A Moulton; Igor Elman; Lino R Becerra; Rita Z Goldstein; David Borsook
Journal:  Addict Biol       Date:  2014-05       Impact factor: 4.280

7.  Effects of cigarette smoking history on neurocognitive recovery over 8 months of abstinence in alcohol-dependent individuals.

Authors:  Timothy C Durazzo; David L Pennington; Thomas P Schmidt; Dieter J Meyerhoff
Journal:  Alcohol Clin Exp Res       Date:  2014-10-21       Impact factor: 3.455

8.  White matter integrity as a link in the association between motivation to abstain and treatment outcome in adolescent substance users.

Authors:  Tammy Chung; Stefan Pajtek; Duncan B Clark
Journal:  Psychol Addict Behav       Date:  2012-02-27

9.  Volumetric differences in the anterior cingulate cortex prospectively predict alcohol-related problems in adolescence.

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Journal:  Psychopharmacology (Berl)       Date:  2014-02-20       Impact factor: 4.530

10.  Neural correlates of impulsivity in healthy males and females with family histories of alcoholism.

Authors:  Elise E DeVito; Shashwath A Meda; Rachel Jiantonio; Marc N Potenza; John H Krystal; Godfrey D Pearlson
Journal:  Neuropsychopharmacology       Date:  2013-04-12       Impact factor: 7.853
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