| Literature DB >> 19682898 |
Yongqi Deng1, Gerald W Shipps, Tong Wang, Janeta Popovici-Muller, Kristin E Rosner, M Arshad Siddiqui, Jose Duca, Alan B Cooper, Michael Cable.
Abstract
A series of 4H-pyrazolo[1,5-a]pyrimidin-7-one derivatives was synthesized and evaluated for inhibitory activity against HCV NS5B RNA-dependent RNA polymerase. A number of these compounds exhibited potent activity in enzymatic assay. The synthesis and structure-activity relationship are also described.Entities:
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Year: 2009 PMID： 19682898 DOI： 10.1016/j.bmcl.2009.07.124
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823