Literature DB >> 19681693

Artemether-lumefantrine: an oral antimalarial for uncomplicated malaria in children.

George O Adjei1, Bamenla Q Goka, Fred Binka, Jorgen Al Kurtzhals.   

Abstract

Artemether-lumefantrine (AL; Coartem, Riamet) is the first fixed-dose artemisinin combination therapy (ACT) regimen to be manufactured under Good Manufacturing Practice conditions, and is the most widely adopted ACT regimen used in malaria control programs. AL is approved for the treatment of uncomplicated malaria in adults, children and infants, and as treatment of uncomplicated malaria in nonimmune travelers returning from malarious areas. AL is efficacious for treating uncomplicated malaria in children and the frequency of associated adverse events is not higher than other available ACT regimens. In this review, available evidence on efficacy and safety of AL in the treatment of uncomplicated malaria, with emphasis on children where appropriate, and focusing on characteristics that are potentially important for malaria control policy decisions, are presented and discussed.

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Year:  2009        PMID： 19681693     DOI： 10.1586/eri.09.53

Source DB:  PubMed          Journal:  Expert Rev Anti Infect Ther        ISSN： 1478-7210            Impact factor:   5.091


  10 in total

1.  Pharmacokinetics of a novel sublingual spray formulation of the antimalarial drug artemether in African children with malaria.

Authors:  Sam Salman; Daryl Bendel; Toong C Lee; David Templeton; Timothy M E Davis
Journal:  Antimicrob Agents Chemother       Date:  2015-03-23       Impact factor: 5.191

Review 2.  Treating uncomplicated malaria in children: comparing artemisinin-based combination therapies.

Authors:  Adoke Yeka; Jamal C Harris
Journal:  Curr Opin Pediatr       Date:  2010-12       Impact factor: 2.856

3.  Efficacy of a novel sublingual spray formulation of artemether in African children with Plasmodium falciparum malaria.

Authors:  Daryl Bendel; Stephen Rulisa; Patrick Ansah; Sodiomon Sirima
Journal:  Antimicrob Agents Chemother       Date:  2015-08-24       Impact factor: 5.191

4.  Adverse reaction to Coartem (artemether/lumefantrine) resulting in oculogyric crisis.

Authors:  Emmanuel Kofi Amponsah; Buyanbileg Sodnom-Ish; Aaron Sowah Anyetei-Anum; Paul Frimpong; Soung Min Kim
Journal:  Maxillofac Plast Reconstr Surg       Date:  2021-05-17

5.  Surveillance for the safety and effectiveness of artemether-lumefantrine in patients with uncomplicated Plasmodium falciparum malaria in the USA: a descriptive analysis.

Authors:  Alyson M Gray; Paul M Arguin; Kamal Hamed
Journal:  Malar J       Date:  2015-09-17       Impact factor: 2.979

6.  Increased systemic exposures of artemether and dihydroartemisinin in infants under 5 kg with uncomplicated Plasmodium falciparum malaria treated with artemether-lumefantrine (Coartem®).

Authors:  Alfred B Tiono; Halidou Tinto; Maroufou J Alao; Martin Meremikwu; Antoinette Tshefu; Bernhards Ogutu; Alphonse Ouedraogo; Moussa Lingani; Marc Cousin; Gilbert Lefèvre; Jay Prakash Jain; Stephan Duparc; Kamal Hamed
Journal:  Malar J       Date:  2015-04-15       Impact factor: 2.979

7.  A randomized trial of artesunate-amodiaquine versus artemether-lumefantrine in Ghanaian paediatric sickle cell and non-sickle cell disease patients with acute uncomplicated malaria.

Authors:  George O Adjei; Bamenla Q Goka; Christabel C Enweronu-Laryea; Onike P Rodrigues; Lorna Renner; Abdul M Sulley; Michael Alifrangis; Insaf Khalil; Jorgen A Kurtzhals
Journal:  Malar J       Date:  2014-09-19       Impact factor: 2.979

8.  Prevalence of malaria among febrile patients and assessment of efficacy of artemether-lumefantrine and artesunate-amodiaquine for uncomplicated malaria in Dolisie, Republic of the Congo.

Authors:  Brice Pembet Singana; Prisca Nadine Casimiro; Brunelle Matondo Diassivi; Simon Charles Kobawila; Jean-Mermoz Youndouka; Leonardo K Basco; Pascal Ringwald; Sébastien Briolant; Mathieu Ndounga
Journal:  Malar J       Date:  2022-05-02       Impact factor: 3.469

9.  A simple and precise method for quantitative analysis of lumefantrine by planar chromatography.

Authors:  Purnima Hamrapurkar; Mitesh Phale; Sandeep Pawar; Priti Patil; Mittal Gandhi
Journal:  Pharm Methods       Date:  2010-10

10.  Development of a dissolution method for lumefantrine and artemether in immediate release fixed dose artemether/lumefantrine tablets.

Authors:  Sileshi Belew; Sultan Suleman; Markos Duguma; Henok Teshome; Evelien Wynendaele; Luc Duchateau; Bart De Spiegeleer
Journal:  Malar J       Date:  2020-04-07       Impact factor: 2.979
  10 in total

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