OBJECTIVE: to determine the simultaneous presence of H. pylori in both the oral cavity and gastric mucosal in patients suffering digestive pathologies and to establish the possible association between the presence of H. pylori in the oral cavity and the gingivoperiodontal pathology. STUDY DESIGN: Patients with gastric symptoms (case group) and asymptomatic patients (control group) seen at the Gastroenterology Department of Dr. Julio C. Perrando Hospital (Resistencia, Argentina) were selected. Dental plaque and saliva samples from both groups were obtained. In the case group, gastric biopsy samples were also taken. H. pylori was detected in gastric biopsies by histological stains, and Polymerase Chain Reaction (PCR) was carried out on the oral samples. RESULTS: Among the 98 patients (43 cases and 55 controls), 196 oral samples (saliva 98, dental plaque 98) and 43 gastric biopsias were obtained. H. pylori was detected in oral samples in 18/98 patients, in gastric biopsies in 38/43 patients, and in both samples in 15/43 patients. CONCLUSIONS: The presence of H. pylori in the oral cavity of patients suffering digestive pathologies is more frequent in those patients harbouring a gingivoperiodontal disease, and this fact could represent an obstacle for the eradication of the bacterium. At the same time, it could constitute a risk factor for gastrointestinal reinfection after treatment.
OBJECTIVE: to determine the simultaneous presence of H. pylori in both the oral cavity and gastric mucosal in patients suffering digestive pathologies and to establish the possible association between the presence of H. pylori in the oral cavity and the gingivoperiodontal pathology. STUDY DESIGN:Patients with gastric symptoms (case group) and asymptomatic patients (control group) seen at the Gastroenterology Department of Dr. Julio C. Perrando Hospital (Resistencia, Argentina) were selected. Dental plaque and saliva samples from both groups were obtained. In the case group, gastric biopsy samples were also taken. H. pylori was detected in gastric biopsies by histological stains, and Polymerase Chain Reaction (PCR) was carried out on the oral samples. RESULTS: Among the 98 patients (43 cases and 55 controls), 196 oral samples (saliva 98, dental plaque 98) and 43 gastric biopsias were obtained. H. pylori was detected in oral samples in 18/98 patients, in gastric biopsies in 38/43 patients, and in both samples in 15/43 patients. CONCLUSIONS: The presence of H. pylori in the oral cavity of patients suffering digestive pathologies is more frequent in those patients harbouring a gingivoperiodontal disease, and this fact could represent an obstacle for the eradication of the bacterium. At the same time, it could constitute a risk factor for gastrointestinal reinfection after treatment.
Authors: Isabel Adler; Andrea Muiño; Silvia Aguas; Laura Harada; Mariana Diaz; Adriana Lence; Mario Labbrozzi; Juan Manuel Muiño; Boris Elsner; Alejandra Avagnina; Valeria Denninghoff Journal: World J Gastroenterol Date: 2014-08-07 Impact factor: 5.742
Authors: B Mesquita; M J Gonçalves; P Pacheco; J Lopes; F Salazar; M Relvas; C Coelho; J J Pacheco; C Velazco Journal: Curr Microbiol Date: 2014-04-09 Impact factor: 2.188
Authors: Nélio Veiga; Carlos Pereira; Carlos Resende; Odete Amaral; Manuela Ferreira; Paula Nelas; Claudia Chaves; João Duarte; Luis Cirnes; José Carlos Machado; Paula Ferreira; Ilídio J Correia Journal: PLoS One Date: 2015-05-26 Impact factor: 3.240