Literature DB >> 19679968

Frontal recurrence of medulloblastoma five years after excision and craniospinal irradiation.

Y B Roka1, P Bista, G R Sharma, D Adhikari, P Kumar.   

Abstract

Medulloblastomas were originally classified under gliomas of the cerebellum until Bailey and Cushing in 1925 named these tumors as medulloblastoma. At present these tumors are classified under primitive neuroectodermal tumor. Surgical excision followed by craniospinal irradiation is the treatment of choice. A 13-year-old-girl operated for posterior fossa medulloblastoma 5 years ago presented with history of headache and vomiting on and off for 4 days in late August 2008. The MRI showed left frontal tumor which on excision was reported as medulloblastoma. Even after optimal treatment reports of recurrence abound in literature. The most common location is in the posterior fossa, followed by spinal, supratentorial, and uncommonly, systemic metastases. We conclude that medulloblastomas are highly aggressive tumor with high local recurrences if the initial excision is incomplete and that recurrence in the supratentorial area although uncommon is still a possibility. This mandates regular follow up of these children till adulthood to catch early recurrences and metastatic disease.

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Year:  2009        PMID: 19679968     DOI: 10.4103/0377-4929.55001

Source DB:  PubMed          Journal:  Indian J Pathol Microbiol        ISSN: 0377-4929            Impact factor:   0.740


  4 in total

Review 1.  Subfrontal recurrence after cerebellar medulloblastoma resection without local relapse: case-based update.

Authors:  He Yue; Wang Ling; Ou Yibo; Wang Sheng; Tang Sicheng; Chen Jincao; Guo Dongsheng
Journal:  Childs Nerv Syst       Date:  2018-06-23       Impact factor: 1.475

2.  Remote Supratentorial Recurrent Medulloblastoma: Case Study and Literature Review.

Authors:  Asimina Dominari; Elias Antoniades; Antonio Capiccelo; Emmanuil Hatzipantelis; Nikolaos Foroglou
Journal:  Asian J Neurosurg       Date:  2022-08-24

3.  Supratentorial metastasis of medulloblastoma in adults.

Authors:  Sushil Kumar; Amit Handa; Deepak K Jha; Ajay Choudhary
Journal:  Asian J Neurosurg       Date:  2016 Jul-Sep

4.  Isolated Supratentorial Intraventricular Recurrence of Medulloblastoma.

Authors:  Kingsley O Abode-Iyamah; Nolan Winslow; Oliver Flouty; Patricia Kirby
Journal:  J Korean Neurosurg Soc       Date:  2015-12-31
  4 in total

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