Literature DB >> 19679066

IGF-1: elixir for motor neuron diseases.

Theodora Papanikolaou1, Lisa M Ellerby.   

Abstract

Modulation of testosterone levels is a therapeutic approach for spinal and bulbar muscular atrophy (SBMA), a polyglutamine disorder that affects the motor neurons. The article by Palazzolo et al. in this issue of Neuron provides compelling evidence that the expression of insulin growth hormone is a potential therapeutic for SBMA.

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Year:  2009        PMID： 19679066     DOI： 10.1016/j.neuron.2009.07.024

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  2 in total

1.  The metabolic and endocrine characteristics in spinal and bulbar muscular atrophy.

Authors:  Angela Rosenbohm; Susanne Hirsch; Alexander E Volk; Torsten Grehl; Julian Grosskreutz; Frank Hanisch; Andreas Herrmann; Katja Kollewe; Wolfram Kress; Thomas Meyer; Susanne Petri; Johannes Prudlo; Carsten Wessig; Hans-Peter Müller; Jens Dreyhaupt; Jochen Weishaupt; Christian Kubisch; Jan Kassubek; Patrick Weydt; Albert C Ludolph
Journal:  J Neurol       Date:  2018-02-20       Impact factor: 4.849

Review 2.  Clinical Trials in Spinal and Bulbar Muscular Atrophy-Past, Present, and Future.

Authors:  Patrick Weydt; Anna Sagnelli; Angela Rosenbohm; Pietro Fratta; Pierre-François Pradat; Albert C Ludolph; Davide Pareyson
Journal:  J Mol Neurosci       Date:  2015-11-14       Impact factor: 3.444
  2 in total

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