AIM: The aim of this study was to test a new collagen matrix (CM) aimed to increase keratinized gingiva/mucosa when compared with the free connective tissue graft (CTG). MATERIAL AND METHODS: This randomized longitudinal parallel controlled clinical trial studied 20 patients with at least one location with minimal keratinized tissue (<or=1 mm). MAIN OUTCOME MEASURE: The 6-month width of keratinized tissue. As secondary outcomes, the aesthetic outlook, the maintenance of periodontal health and the patient morbidity were assessed pre-operatively at 1, 3 and 6 months. RESULTS: At 6 months, the CTG attained a mean width of keratinized tissue of 2.6 (0.9) mm, while the CM was 2.5 (0.9) mm, these differences being insignificant. In both groups, there was a marked contraction (60% and 67%, respectively) although the periodontal parameters were not affected. The CM group had a significantly lower patient morbidity (pain and medication intake) as well as reduced surgery time. CONCLUSIONS: These results prove that this new CM was as effective and predictable as the CTG for attaining a band of keratinized tissue, but its use was associated with a significantly lower patient morbidity.
RCT Entities:
AIM: The aim of this study was to test a new collagen matrix (CM) aimed to increase keratinized gingiva/mucosa when compared with the free connective tissue graft (CTG). MATERIAL AND METHODS: This randomized longitudinal parallel controlled clinical trial studied 20 patients with at least one location with minimal keratinized tissue (<or=1 mm). MAIN OUTCOME MEASURE: The 6-month width of keratinized tissue. As secondary outcomes, the aesthetic outlook, the maintenance of periodontal health and the patient morbidity were assessed pre-operatively at 1, 3 and 6 months. RESULTS: At 6 months, the CTG attained a mean width of keratinized tissue of 2.6 (0.9) mm, while the CM was 2.5 (0.9) mm, these differences being insignificant. In both groups, there was a marked contraction (60% and 67%, respectively) although the periodontal parameters were not affected. The CM group had a significantly lower patient morbidity (pain and medication intake) as well as reduced surgery time. CONCLUSIONS: These results prove that this new CM was as effective and predictable as the CTG for attaining a band of keratinized tissue, but its use was associated with a significantly lower patient morbidity.
Authors: Daniel S Thoma; AbdulMonem Alshihri; Alain Fontolliet; Christoph H F Hämmerle; Ronald E Jung; Goran I Benic Journal: Clin Oral Investig Date: 2017-12-22 Impact factor: 3.573
Authors: Jonas Lorenz; Maximilian Blume; Mike Barbeck; Anna Teiler; C James Kirkpatrick; Robert A Sader; Shahram Ghanaati Journal: Clin Oral Investig Date: 2016-06-16 Impact factor: 3.573
Authors: Marco Esposito; Hassan Maghaireh; Maria Gabriella Grusovin; Ioannis Ziounas; Helen V Worthington Journal: Cochrane Database Syst Rev Date: 2012-02-15