Literature DB >> 1967668

Hypothesis: Helicobacter pylori, urease, mucus, and gastric ulcer.

R L Sidebotham1, J H Baron.   

Abstract

Ammonia, released in the gastric mucosa by the action of Helicobacter pylori urease on transuded plasma urea, curtails the biosynthesis of mucus and/or causes the mucus to be disassembled at the mucosal surface. These changes facilitate colonisation by H pylori and may promote gastric ulcer formation.

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Year:  1990        PMID: 1967668     DOI: 10.1016/0140-6736(90)90279-e

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  19 in total

Review 1.  Urease-positive thermophilic Campylobacter species.

Authors:  Motoo Matsuda; John E Moore
Journal:  Appl Environ Microbiol       Date:  2004-08       Impact factor: 4.792

Review 2.  Gastroenterology.

Authors:  L J O'Donnell; E M Alstead; M J Farthing
Journal:  Postgrad Med J       Date:  1990-06       Impact factor: 2.401

3.  Ammonia, hydrogen peroxide, and monochloramine retard gastric epithelial restoration in rabbit cultured cell model.

Authors:  K Sato; S Watanabe; T Yoshizawa; M Hirose; T Murai; N Sato
Journal:  Dig Dis Sci       Date:  1999-12       Impact factor: 3.199

Review 4.  Helicobacter pylori and peptic ulcers: the present position.

Authors:  S Moss; J Calam
Journal:  Gut       Date:  1992-03       Impact factor: 23.059

5.  Isolation of "Helicobacter heilmannii" from human tissue.

Authors:  S L Hazell
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1996-01       Impact factor: 3.267

6.  Helicobacter pylori associated phospholipase A2 activity: a factor in peptic ulcer production?

Authors:  S R Langton; S D Cesareo
Journal:  J Clin Pathol       Date:  1992-03       Impact factor: 3.411

7.  Preparation and characterization of freeze-dried chitosan-poly(ethylene oxide) hydrogels for site-specific antibiotic delivery in the stomach.

Authors:  V R Patel; M M Amiji
Journal:  Pharm Res       Date:  1996-04       Impact factor: 4.200

8.  Neutrophil activation by Helicobacter pylori.

Authors:  C Mooney; J Keenan; D Munster; I Wilson; R Allardyce; P Bagshaw; B Chapman; V Chadwick
Journal:  Gut       Date:  1991-08       Impact factor: 23.059

9.  Peptic ulcer surgery in patients with liver cirrhosis.

Authors:  T Lehnert; C Herfarth
Journal:  Ann Surg       Date:  1993-04       Impact factor: 12.969

10.  Purification and characterization of the urease enzymes of Helicobacter species from humans and animals.

Authors:  G R Turbett; P B Høj; R Horne; B J Mee
Journal:  Infect Immun       Date:  1992-12       Impact factor: 3.441

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