Literature DB >> 19674567

Phytochemicals & cancer.

Jerrold J Simon1.   

Abstract

BACKGROUND: Although traditionally cancer has been fought with the usual armamentarium of chemotherapy and high doses of directed radiation, lately there has been more attention devoted to combating cancer through nutritive means. In particular, certain phytochemicals including some vitamins, some minerals and a wide range of other bioactive nutrients have been found useful in the physiological battle against cancer.
OBJECTIVE: The objective of this article is to determine which vitamins, minerals and bioactive nutrients may be useful in combating cancer and to give therapeutic dosages of such when known. DATA SYNTHESIS: The scientific literature is replete with research documenting the link between certain nutritional protocols and inhibition or protection against the disease of cancer. From the landmark article entitled The Causes of Cancer by Richard Doll and Richard Peto which was first commissioned as a report to the Office of Technology Assessment of the United States Congress to the American Cancer Societys Advisory Committee Guidelines on Diet, Nutrition and Cancer Prevention: Reducing the Risk of Cancer with Health Food Choices and Physical Activity, the nutritional literature continues to provide the necessary link for the clinician to justifiably advise patients regarding proper dietary habits in order reduce the patients risk of cancer.
RESULTS: Although there has been much research regarding the relationship between vitamins, minerals and other bioactive phytonutrients and cancer and protection against cancer, not all of the literature supports a strong and convincing link between the nutrient and cancer protection. This article differentiates the convincing evidence vs. the probable and the possible evidence of the link between the nutrient and its inhibitive effect on cancer.
CONCLUSION: Certain vitamins, minerals and bioactive phytonutrients can be used as a first line of therapeutic defense against cancer before chemotherapy and radiation treatment is commenced.

Entities:  

Year:  2002        PMID: 19674567      PMCID: PMC2646927          DOI: 10.1016/S0899-3467(07)60010-X

Source DB:  PubMed          Journal:  J Chiropr Med        ISSN: 1556-3707


  12 in total

Review 1.  Evolution of glutathione metabolism.

Authors:  R C Fahey; A R Sundquist
Journal:  Adv Enzymol Relat Areas Mol Biol       Date:  1991

2.  The role of soy products in reducing risk of cancer.

Authors:  M Messina; S Barnes
Journal:  J Natl Cancer Inst       Date:  1991-04-17       Impact factor: 13.506

3.  Guidelines on diet, nutrition, and cancer prevention: reducing the risk of cancer with healthy food choices and physical activity. The American Cancer Society 1996 Advisory Committee on Diet, Nutrition, and Cancer Prevention.

Authors: 
Journal:  CA Cancer J Clin       Date:  1996 Nov-Dec       Impact factor: 508.702

Review 4.  A global view of human selenium nutrition.

Authors:  O A Levander
Journal:  Annu Rev Nutr       Date:  1987       Impact factor: 11.848

5.  Protective effect of plant sterols against chemically induced colon tumors in rats.

Authors:  R F Raicht; B I Cohen; E P Fazzini; A N Sarwal; M Takahashi
Journal:  Cancer Res       Date:  1980-02       Impact factor: 12.701

Review 6.  Chemoprevention of oral cancer: beta-carotene and vitamin E in leukoplakia.

Authors:  H Garewal
Journal:  Eur J Cancer Prev       Date:  1994-03       Impact factor: 2.497

7.  Carotenoid content of fruits and vegetables: an evaluation of analytic data.

Authors:  A R Mangels; J M Holden; G R Beecher; M R Forman; E Lanza
Journal:  J Am Diet Assoc       Date:  1993-03

8.  Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles.

Authors:  L W Wattenberg; W D Loub
Journal:  Cancer Res       Date:  1978-05       Impact factor: 12.701

Review 9.  Can dietary beta-carotene materially reduce human cancer rates?

Authors:  R Peto; R Doll; J D Buckley; M B Sporn
Journal:  Nature       Date:  1981-03-19       Impact factor: 49.962

10.  Food items and food groups as risk factors in a case-control study of diet and colo-rectal cancer.

Authors:  A B Miller; G R Howe; M Jain; K J Craib; L Harrison
Journal:  Int J Cancer       Date:  1983-08-15       Impact factor: 7.396

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  1 in total

Review 1.  Phytochemicals in the Fight Against Cancer.

Authors:  Kristoffer T Davidson; Ziwen Zhu; Yujiang Fang
Journal:  Pathol Oncol Res       Date:  2016-02-09       Impact factor: 3.201

  1 in total

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