Literature DB >> 19674503

Molecular neurodevelopment: an in vivo 31P-1H MRSI study.

Gerald Goldstein1, Kanagasabai Panchalingam, Richard J McClure, Jeffrey A Stanley, Vince D Calhoun, Godfrey D Pearlson, Jay W Pettegrew.   

Abstract

Synaptic development and elimination are normal neurodevelopmental processes, which if altered could contribute to various neuropsychiatric disorders. 31P-1H magnetic resonance spectroscopic imaging (MRSI) and structural magnetic resonance imaging (MRI) exams were conducted on 105 healthy children ages 6-18 years old to identify neuromolecular indices of synaptic development and elimination. Over the age range studied, age-related changes in high-energy phosphate (phosphocreatine), membrane phospholipid metabolism (precursors and breakdown products), and percent gray matter volume were found. These neuromolecular and structural indices of synaptic development and elimination are associated with development of several cognitive domains. Monitoring of these molecular markers is essential for devising treatment strategies for neurodevelopmental disorders.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19674503      PMCID： PMC2773163          DOI： 10.1017/S1355617709990233

Source DB:  PubMed          Journal:  J Int Neuropsychol Soc        ISSN： 1355-6177            Impact factor:   2.892


  58 in total

1.  Postprocessing method to segregate and quantify the broad components underlying the phosphodiester spectral region of in vivo (31)P brain spectra.

Authors:  J A Stanley; J W Pettegrew
Journal:  Magn Reson Med       Date:  2001-03       Impact factor: 4.668

2.  Comparison of the quantification precision of human short echo time (1)H spectroscopy at 1.5 and 4.0 Tesla.

Authors:  R Bartha; D J Drost; R S Menon; P C Williamson
Journal:  Magn Reson Med       Date:  2000-08       Impact factor: 4.668

Review 3.  Advances in functional and structural MR image analysis and implementation as FSL.

Authors:  Stephen M Smith; Mark Jenkinson; Mark W Woolrich; Christian F Beckmann; Timothy E J Behrens; Heidi Johansen-Berg; Peter R Bannister; Marilena De Luca; Ivana Drobnjak; David E Flitney; Rami K Niazy; James Saunders; John Vickers; Yongyue Zhang; Nicola De Stefano; J Michael Brady; Paul M Matthews
Journal:  Neuroimage       Date:  2004       Impact factor: 6.556

4.  Bayesian analysis of neuroimaging data in FSL.

Authors:  Mark W Woolrich; Saad Jbabdi; Brian Patenaude; Michael Chappell; Salima Makni; Timothy Behrens; Christian Beckmann; Mark Jenkinson; Stephen M Smith
Journal:  Neuroimage       Date:  2008-11-13       Impact factor: 6.556

5.  Some properties of synaptic membranes isolated from the central nervous system.

Authors:  V P Whittaker
Journal:  Ann N Y Acad Sci       Date:  1966-07-14       Impact factor: 5.691

6.  The subcellular localization of gangliosides in the brain.

Authors:  H Wiegandt
Journal:  J Neurochem       Date:  1967-06       Impact factor: 5.372

7.  Cerebral circulatory and metabolic changes associated with aging.

Authors:  L Sokoloff
Journal:  Res Publ Assoc Res Nerv Ment Dis       Date:  1966

8.  Tay-Sachs disease. A generalized metabolic disorder.

Authors:  L Eeg-Olofsson; K Kristensson; P Sourander; L Svennerholm
Journal:  Acta Paediatr Scand       Date:  1966-11

9.  The pattern of mammalian brain gangliosides. 3. Regional and developmental differences.

Authors:  K Suzaki
Journal:  J Neurochem       Date:  1965-12       Impact factor: 5.372

10.  Parameterized evaluation of macromolecules and lipids in proton MR spectroscopy of brain diseases.

Authors:  Uwe Seeger; Uwe Klose; Irina Mader; Wolfgang Grodd; Thomas Nägele
Journal:  Magn Reson Med       Date:  2003-01       Impact factor: 4.668
View more
  9 in total

Review 1.  Developmental trajectories during adolescence in males and females: a cross-species understanding of underlying brain changes.

Authors:  Heather C Brenhouse; Susan L Andersen
Journal:  Neurosci Biobehav Rev       Date:  2011-05-12       Impact factor: 8.989

2.  Neuropil pruning in Early-Course Schizophrenia: Immunological, Clinical, and Neurocognitive Correlates.

Authors:  Konasale M Prasad; Ashley M Burgess; Matcheri S Keshavan; Vishwajit L Nimgaonkar; Jeffrey A Stanley
Journal:  Biol Psychiatry Cogn Neurosci Neuroimaging       Date:  2016-11

Review 3.  Genetic influences on brain developmental trajectories on neuroimaging studies: from infancy to young adulthood.

Authors:  Vanessa Douet; Linda Chang; Christine Cloak; Thomas Ernst
Journal:  Brain Imaging Behav       Date:  2014-06       Impact factor: 3.978

4.  Altered development of the dorsolateral prefrontal cortex in chromosome 22q11.2 deletion syndrome: an in vivo proton spectroscopy study.

Authors:  Vandana Shashi; Aravindhan Veerapandiyan; Matcheri S Keshavan; Michael Zapadka; Kelly Schoch; Thomas R Kwapil; Stephen R Hooper; Jeffrey A Stanley
Journal:  Biol Psychiatry       Date:  2012-05-25       Impact factor: 13.382

5.  Cortical surface characteristics among offspring of schizophrenia subjects.

Authors:  Konasale M Prasad; Dhruman Goradia; Shaun Eack; Malolan Rajagopalan; Jeffrey Nutche; Tara Magge; Rajaprabhakaran Rajarethinam; Matcheri S Keshavan
Journal:  Schizophr Res       Date:  2009-12-04       Impact factor: 4.939

6.  Sleep spindle activity and cognitive performance in healthy children.

Authors:  Alex Chatburn; Scott Coussens; Kurt Lushington; Declan Kennedy; Mathias Baumert; Mark Kohler
Journal:  Sleep       Date:  2013-02-01       Impact factor: 5.849

7.  Evaluation of a New 1H/31P Dual-Tuned Birdcage Coil for 31P Spectroscopy.

Authors:  Wm Potter; L Wang; Kk McCully; Q Zhao
Journal:  Concepts Magn Reson Part B Magn Reson Eng       Date:  2013-08-01       Impact factor: 1.176

Review 8.  Contributions of magnetic resonance spectroscopy to understanding development: potential applications in the study of adolescent alcohol use and abuse.

Authors:  Julia E Cohen-Gilbert; J Eric Jensen; Marisa M Silveri
Journal:  Dev Psychopathol       Date:  2014-03-12

9.  Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.

Authors:  Konasale M Prasad; Kodavali V Chowdari; Leonardo A D'Aiuto; Satish Iyengar; Jeffrey A Stanley; Vishwajit L Nimgaonkar
Journal:  Transl Psychiatry       Date:  2018-07-19       Impact factor: 6.222
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.