Histologic types of bronchogenic cancer in relation to different conditions of radiation exposure.

The rish of lung cancer among the uranium miner study group was found to be not only connected with the increase in frequency of different histologic types of lung cancer, but mainly with the increase of small cell undifferentiated and epidermoid type frequencies. It appears that the frequency of these two major histologic types may be influenced by the level of cumulated radiation exposure and by the time course of cumulation of exposure in a different way. These findings, in agreement wit recent data of Archer et al., eliminate the former assumption that radiation can induce an elevated frequency of only one histologic type of lung cancer.