What do we know of post-thrombotic syndrome? Current status of post-thrombotic syndrome in adults.

The post-thrombotic syndrome (PTS) is a common but not completely understood and rarely studied sequela of an acute deep vein thrombosis. The influence of several risk factors on the incidence or severity of PTS is controversial. The therapeutic options for PTS are still limited. Appropriate medical compression stockings can reduce the incidence (-50 %) as well as the severity of PTS. In the case of severe, symptomatic PTS, they should be worn lifelong. As PTS is a chronic and often progressive disease, patients need regular clinical follow-up and encouragement to continuously wear their compression therapy. New strategies for treating PTS are needed.