Literature DB >> 19671517

Radioactivity and thyroid cancer.

Christopher Reiners1.   

Abstract

There is no evidence that natural radiation (cosmic radiation or from natural radioiosotopes) increases the risk for thyroid diseases. Moreover, while it has been proven that exposure to external medical radiation or to external and internal radiation by atomic bomb explosions leads to an increased risk for thyroid cancer, the medical use of radioiodine, namely diagnostic and therapeutic application of (1)(3)(1)I, is safe and does not induce thyroid cancer. Exposure of children aged less than 4 years to fallout from the Chernobyl reactor accident has led to a substantial increase of childhood cancer incidence in the countries affected (Belarus, Ukraine and Western parts of Russia). Up to now, the total number of cases in children and adolescents adds up to approximately 5,000; in the next 50 years, approximately 15,000 additional thyroid cancer cases in this age group are expected. With respect to the Chernobyl effects on adults, there is no proven radiation related increase of the thyroid cancer incidence. As can be proven by a therapy project in 247 children with advanced thyroid cancer from Belarus, the prognosis for this tumor, even when metastasized, is good, this being in accordance with literature data indicating mortality rates between 1 and 2%.

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Year:  2009        PMID: 19671517     DOI: 10.14310/horm.2002.1234

Source DB:  PubMed          Journal:  Hormones (Athens)        ISSN: 1109-3099            Impact factor:   2.885


  7 in total

1.  Thyroid cancer after chernobyl: obfuscated truth.

Authors:  Sergei V Jargin
Journal:  Dose Response       Date:  2011-02-25       Impact factor: 2.658

2.  Papillary thyroid carcinoma does not have standard course in children.

Authors:  Ibrahim Karnak; Burak Ardıçlı; Saniye Ekinci; Arbay Ozden Ciftçi; Diclehan Orhan; Gülsev Kale; Feridun Cahit Tanyel; Mehmet Emin Senocak
Journal:  Pediatr Surg Int       Date:  2011-05-24       Impact factor: 1.827

3.  EANM procedure guidelines for therapy of benign thyroid disease.

Authors:  Marcel P M Stokkel; Daria Handkiewicz Junak; Michael Lassmann; Markus Dietlein; Markus Luster
Journal:  Eur J Nucl Med Mol Imaging       Date:  2010-07-13       Impact factor: 9.236

4.  Thyroid Cancer: We Need a Carcinogen-specific Genome Study.

Authors:  Jong-Myon Bae
Journal:  J Korean Med Sci       Date:  2015-11-30       Impact factor: 2.153

5.  Single neonatal irradiation induces long-term gene expression changes in the thyroid gland, which may be involved in the tumorigenesis.

Authors:  Nariaki Fujimoto; Mutsumi Matsuu-Matsuyama; Masahiro Nakashima
Journal:  Sci Rep       Date:  2021-12-08       Impact factor: 4.379

6.  Clinical and molecular characterization of thyroid cancer when seen as a second malignant neoplasm.

Authors:  Kristen Romanelli; Justin Wells; Aneeta Patel; Maria Mendonca Torres; John Costello; Kirk Jensen; Vasyl Vasko
Journal:  Ther Adv Endocrinol Metab       Date:  2021-11-24       Impact factor: 3.565

7.  Are risk factors common to thyroid cancer and nodule? A forty years observational time-trend study.

Authors:  Angelo Carpi; Giuseppe Rossi; Rossana Romani; Giancarlo Di Coscio; Andrea Nicolini; Tommaso Simoncini; Matteo Russo; Jeffrey Mechanick
Journal:  PLoS One       Date:  2012-10-31       Impact factor: 3.240

  7 in total

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