Literature DB >> 1967151

A subpopulation of the avian erythroblastosis virus v-erbA protein, a member of the nuclear hormone receptor family, is glycosylated.

M L Privalsky1.   

Abstract

The v-erbA oncogene of avian erythroblastosis virus is derived from a cellular gene for a thyroid hormone (T4/T3 thyronine) receptor and encodes a DNA-binding protein found principally in the nucleus of the infected cell. I report here that a subpopulation of the v-erbA protein is glycosylated. The v-erbA protein, therefore, is another member of the newly recognized family of eucaryotic transcription factors and related polypeptides which are glycoproteins.

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Year:  1990        PMID: 1967151      PMCID: PMC249128     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  14 in total

1.  c-erbA encodes multiple proteins in chicken erythroid cells.

Authors:  J Bigler; R N Eisenman
Journal:  Mol Cell Biol       Date:  1988-10       Impact factor: 4.272

2.  v-erbA cooperates with sarcoma oncogenes in leukemic cell transformation.

Authors:  P Kahn; L Frykberg; C Brady; I Stanley; H Beug; B Vennström; T Graf
Journal:  Cell       Date:  1986-05-09       Impact factor: 41.582

3.  Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist.

Authors:  K Damm; C C Thompson; R M Evans
Journal:  Nature       Date:  1989-06-22       Impact factor: 49.962

4.  v-erbA specifically suppresses transcription of the avian erythrocyte anion transporter (band 3) gene.

Authors:  M Zenke; P Kahn; C Disela; B Vennström; A Leutz; K Keegan; M J Hayman; H R Choi; N Yew; J D Engel
Journal:  Cell       Date:  1988-01-15       Impact factor: 41.582

5.  Expression of the v-erbA oncogene in chicken embryo fibroblasts stimulates their proliferation in vitro and enhances tumor growth in vivo.

Authors:  O Gandrillon; P Jurdic; M Benchaibi; J H Xiao; J Ghysdael; J Samarut
Journal:  Cell       Date:  1987-06-05       Impact factor: 41.582

6.  The c-erb-A protein is a high-affinity receptor for thyroid hormone.

Authors:  J Sap; A Muñoz; K Damm; Y Goldberg; J Ghysdael; A Leutz; H Beug; B Vennström
Journal:  Nature       Date:  1986 Dec 18-31       Impact factor: 49.962

7.  The c-erb-A gene encodes a thyroid hormone receptor.

Authors:  C Weinberger; C C Thompson; E S Ong; R Lebo; D J Gruol; R M Evans
Journal:  Nature       Date:  1986 Dec 18-31       Impact factor: 49.962

8.  Transforming capacities of avian erythroblastosis virus mutants deleted in the erbA or erbB oncogenes.

Authors:  L Frykberg; S Palmieri; H Beug; T Graf; M J Hayman; B Vennström
Journal:  Cell       Date:  1983-01       Impact factor: 41.582

9.  O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation.

Authors:  S P Jackson; R Tjian
Journal:  Cell       Date:  1988-10-07       Impact factor: 41.582

10.  The product of the avian erythroblastosis virus erbB locus is a glycoprotein.

Authors:  M L Privalsky; L Sealy; J M Bishop; J P McGrath; A D Levinson
Journal:  Cell       Date:  1983-04       Impact factor: 41.582

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  2 in total

1.  Intracellular posttranslational modifications of S1133 avian reovirus proteins.

Authors:  R Varela; J Martínez-Costas; M Mallo; J Benavente
Journal:  J Virol       Date:  1996-05       Impact factor: 5.103

2.  Site-specific glycosylation of the human cytomegalovirus tegument basic phosphoprotein (UL32) at serine 921 and serine 952.

Authors:  K D Greis; W Gibson; G W Hart
Journal:  J Virol       Date:  1994-12       Impact factor: 5.103

  2 in total

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