Literature DB >> 19669859

Acute lower limb ischemia in a patient with aortic thrombus and essential thrombocytosis.

P Caridad Morata Barrado1,2, E Blanco Cañibano3, B García Fresnillo3, M Guerra Requena3.   

Abstract

Aortic thrombus is rare in patients with essential thrombocytosis (ET), so the optimal treatment remains undefined. A 45-year-old man with history of ET, under chronic treatment with aspirin, presented to the emergency department complaining of acute onset in both the legs and abdominal pain. Physical examination revealed that both dorsalis pedis pulses were not palpable with cold and pale feet. His abdomen was soft and nondistended. The platelet count was 436 x 10(9)/L. The thoraco-abdominal computerized tomographic scanning revealed normal aortic diameter with supraceliac and infrarenal nonoccluding thrombus and infarction areas in spleen and left kidney. At the emergency department he presented with recurrent symptoms, losing bilateral posterior tibial pulses. A decision was made to perform a thoracoretroperitoneal incision. A longitudinal sequential aortotomy was performed in the distal thoracic and infrarenal aorta, and the thrombus was easily removed. Following this, he underwent bilateral crural thrombectomy and local intra-arterial thrombolytic therapy. The postoperative course was uneventful. The left toes were amputated because of necrosis. He was discharged and put on antiaggregants, anticoagulants and hydroxyurea. Aortic thrombus in patients with ET is unusual, but potentially lethal. There is complete relief from symptoms in recurrent cases following surgery. An appropriate medical treatment after intervention must be supported.

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Year:  2009        PMID: 19669859     DOI: 10.1007/s12185-009-0394-2

Source DB:  PubMed          Journal:  Int J Hematol        ISSN: 0925-5710            Impact factor:   2.490


  20 in total

1.  Splenic-portal- mesenteric thrombosis with splenic infarction as first presentation of essential thrombocytosis.

Authors:  Julio Maria Fonseca Chebli; Pedro Duarte Gaburri; Aécio Flávio Meirelles de Souza; Guilherme Eduardo Gonçalves Felga; Cecília Ganimi Forn; Janine Radd Ferreira Pinto
Journal:  J Clin Gastroenterol       Date:  2004-07       Impact factor: 3.062

2.  Floating thrombus in the proximal aortic arch.

Authors:  Jong Bum Choi; Soon Ho Choi; Nam Ho Kim; Jin Won Jeong
Journal:  Tex Heart Inst J       Date:  2004

3.  Medical management of a large aortic thrombus in a young woman with essential thrombocythemia.

Authors:  M Fang; S Agha; L Lockridge; R Lee; J P Cleary; E M Mazur
Journal:  Mayo Clin Proc       Date:  2001-04       Impact factor: 7.616

4.  Endovascular therapy of a symptomatic mobile thrombus of the thoracic aorta.

Authors:  T Luebke; M Aleksic; J Brunkwall
Journal:  Eur J Vasc Endovasc Surg       Date:  2008-08-23       Impact factor: 7.069

Review 5.  The 2001 World Health Organization and updated European clinical and pathological criteria for the diagnosis, classification, and staging of the Philadelphia chromosome-negative chronic myeloproliferative disorders.

Authors:  Jan J Michiels; Hendrik De Raeve; Zwi Berneman; Dirk Van Bockstaele; Konnie Hebeda; King Lam; Wilfried Schroyens
Journal:  Semin Thromb Hemost       Date:  2006-06       Impact factor: 4.180

6.  Endovascular stent graft for symptomatic mobile thrombus of the thoracic aorta.

Authors:  Philipp Fueglistaler; Thomas Wolff; Lorenz Guerke; Peter Stierli; Thomas Eugster
Journal:  J Vasc Surg       Date:  2005-10       Impact factor: 4.268

7.  Aortic mural thrombus embolization: an unusual presentation of essential thrombocytosis.

Authors:  David R Lorelli; Alexander D Shepard
Journal:  Ann Vasc Surg       Date:  2002-04-18       Impact factor: 1.466

8.  Hydroxyurea for patients with essential thrombocythemia and a high risk of thrombosis.

Authors:  S Cortelazzo; G Finazzi; M Ruggeri; O Vestri; M Galli; F Rodeghiero; T Barbui
Journal:  N Engl J Med       Date:  1995-04-27       Impact factor: 91.245

9.  Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: recommendations from an ad hoc international expert panel.

Authors:  Ayalew Tefferi; Juergen Thiele; Attilio Orazi; Hans Michael Kvasnicka; Tiziano Barbui; Curtis A Hanson; Giovanni Barosi; Srdan Verstovsek; Gunnar Birgegard; Ruben Mesa; John T Reilly; Heinz Gisslinger; Alessandro M Vannucchi; Francisco Cervantes; Guido Finazzi; Ronald Hoffman; D Gary Gilliland; Clara D Bloomfield; James W Vardiman
Journal:  Blood       Date:  2007-05-08       Impact factor: 22.113

10.  Aortic thrombus due to essential thrombocytosis: strategies for medical and surgical management.

Authors:  Vance Sohn; Zachary Arthurs; Charles Andersen; Benjamin Starnes
Journal:  Ann Vasc Surg       Date:  2008-05-22       Impact factor: 1.466

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  1 in total

1.  Essential Thrombocytosis-Associated Thromboembolism in the Abdominal Aorta.

Authors:  Byung Kwon Chong; Dana Mun; Chae Hoon Kang; Chong-Bin Park; Won Chul Cho
Journal:  Korean J Thorac Cardiovasc Surg       Date:  2016-10-05
  1 in total

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