Literature DB >> 19669547

In vitro effects of gamma radiation from 60Co and 137Cs on plasmid DNA.

F M Milian1, A N Gouveia, M R Gual, J O Echeimberg, J D T Arruda-Neto, F Garcia, A C G Schenberg, E J Vicente, O Rodriguez, F Guzman, A Deppman.   

Abstract

The effects of gamma radiation from (60)Co and (137)Cs on DNA in aqueous solution are studied experimentally. Using an improved plasmid purification protocol and improved electrophoretic gel analysis techniques provided results with relatively small uncertainties. The results are compared with both theoretical and experimental results. In particular, the results obtained here are discussed in the light of recent discussion on supposed differences of the effects induced by gamma radiation from (60)Co and (137)Cs. We find that the effects of both types of gamma radiation are similar.

Entities:  

Year:  2008        PMID: 19669547      PMCID: PMC2646396          DOI: 10.1007/s10867-007-9050-3

Source DB:  PubMed          Journal:  J Biol Phys        ISSN: 0092-0606            Impact factor:   1.365


  22 in total

1.  The effect of superhelical density on the yield of single-strand breaks in gamma-irradiated plasmid DNA.

Authors:  J R Milligan; A D Arnold; J F Ward
Journal:  Radiat Res       Date:  1992-10       Impact factor: 2.841

2.  Evaluation of lesion clustering in irradiated plasmid DNA.

Authors:  C Leloup; G Garty; G Assaf; A Cristovão; A Breskin; R Chechik; S Shchemelinin; T Paz-Elizur; Z Livneh; R W Schulte; V Bashkirov; J R Milligan; B Grosswendt
Journal:  Int J Radiat Biol       Date:  2005-01       Impact factor: 2.694

Review 3.  Initial events in the cellular effects of ionizing radiations: clustered damage in DNA.

Authors:  D T Goodhead
Journal:  Int J Radiat Biol       Date:  1994-01       Impact factor: 2.694

4.  The formation of radiation-induced DNA breaks: the ratio of double-strand breaks to single-strand breaks.

Authors:  R Roots; G Kraft; E Gosschalk
Journal:  Int J Radiat Oncol Biol Phys       Date:  1985-02       Impact factor: 7.038

Review 5.  Weiss Lecture. Effects of radiations of different qualities on cells: molecular mechanisms of damage and repair.

Authors:  D T Goodhead; J Thacker; R Cox
Journal:  Int J Radiat Biol       Date:  1993-05       Impact factor: 2.694

6.  Variation of single-strand break yield with scavenger concentration for the SV40 minichromosome irradiated in aqueous solution.

Authors:  J R Milligan; J A Aguilera; J F Ward
Journal:  Radiat Res       Date:  1993-02       Impact factor: 2.841

7.  A comparison of DNA damages produced under conditions of direct and indirect action of radiation.

Authors:  G D Jones; T V Boswell; J Lee; J R Milligan; J F Ward; M Weinfeld
Journal:  Int J Radiat Biol       Date:  1994-11       Impact factor: 2.694

8.  The difference that linear energy transfer makes to precursors of DNA strand breaks.

Authors:  J R Milligan; J A Aguilera; C C Wu; J Y Ng; J F Ward
Journal:  Radiat Res       Date:  1996-04       Impact factor: 2.841

9.  Irradiation of plasmid and phage DNA in water-alcohol mixtures: strand breaks and lethal damage as a function of scavenger concentration.

Authors:  U Klimczak; D C Ludwig; F Mark; P Rettberg; D Schulte-Frohlinde
Journal:  Int J Radiat Biol       Date:  1993-11       Impact factor: 2.694

10.  DNA radiolysis by fast neutrons.

Authors:  M Spotheim-Maurizot; M Charlier; R Sabattier
Journal:  Int J Radiat Biol       Date:  1990-02       Impact factor: 2.694

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  2 in total

1.  Microdosimetry of DNA conformations: relation between direct effect of (60)Co gamma rays and topology of DNA geometrical models in the calculation of A-, B- and Z-DNA radiation-induced damage yields.

Authors:  Farid Semsarha; Gholamreza Raisali; Bahram Goliaei; Hossein Khalafi
Journal:  Radiat Environ Biophys       Date:  2016-03-16       Impact factor: 1.925

2.  Effects of solar particle event proton radiation on parameters related to ferret emesis.

Authors:  J K Sanzari; X S Wan; G S Krigsfeld; G L King; A Miller; R Mick; D S Gridley; A J Wroe; S Rightnar; D Dolney; A R Kennedy
Journal:  Radiat Res       Date:  2013-07-24       Impact factor: 2.841

  2 in total

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