Literature DB >> 19667873

Resuscitation of severely burned military casualties: fluid begets more fluid.

Kevin K Chung1, Steven E Wolf, Leopoldo C Cancio, Ricardo Alvarado, John A Jones, Jeffery McCorcle, Booker T King, David J Barillo, Evan M Renz, Lorne H Blackbourne.   

Abstract

BACKGROUND: In November 2005, institution of a military-wide burn resuscitation guideline requested the documentation of the initial 24-hour resuscitation of severely burned military casualties on a burn flow sheet to provide continuity of care. The guidelines instruct the providers to calculate predicted 24-hour fluid requirements and initial fluid rate based on the American Burn Association Consensus recommendation of 2 (modified Brooke) mL x kg(-1) x % total body surface area (TBSA)(-1) to 4 (Parkland) mL x kg(-1) x %TBSA(-1) burn. The objective of this study was to evaluate the relationship between the estimated fluid volumes calculated, either by the Modified Brooke or the Parkland formulas, and actual volumes received.
METHODS: From November 2005 to December 2008, 105 patients were globally evacuated with >20% TBSA burns, of whom 73 had burn flow sheets initiated. Of these, 58 had completed burn flow sheets. Total fluids administered in the first 24-hour period for each patient were recorded. Chart reviews were performed to extract demographic and clinical outcomes data.
RESULTS: Of the 58, the modified Brooke formula was used in 31 patients (modified Brooke group) to estimate 24-hour fluid requirements and the Parkland formula was used in 21 (Parkland group). In six, 3 mL x kg(-1) x %TBSA(-1) was used and were excluded from analysis. No significant difference was detected between the two groups for age, %TBSA burned, inhalation injury, or Injury Severity Score. Actual 24-hour resuscitation in the modified Brooke group was significantly lower than in the Parkland group (16.9 L +/- 6.0 L vs. 25.0 L +/- 11.2 L, p = 0.003). A greater percentage of patients exceeded the Ivy index (250 mL/kg) in the Parkland group compared with the modified Brooke group (57% vs. 29%, p = 0.026). On average, those who had 24-hour fluid needs estimated by the modified Brooke formula received a 3.8 mL x kg(-1) x %TBSA(-1) +/- 1.2 mL x kg(-1) x %TBSA(-1) resuscitation, whereas the Parkland group received a 5.9 mL x kg(-1) x %TBSA(-1) +/- 1.1 mL x kg(-1) x %TBSA(-1) resuscitation (p < 0.0001). No differences in measured outcomes were detected between the two groups. On multivariate logistic regression, exceeding the Ivy index was an independent predictor of death (area under the curve [AUC], 0.807; CI, 0.66-0.95).
CONCLUSION: In severely burned military casualties undergoing initial burn resuscitation, the modified Brooke formula resulted in significantly less 24-hour volumes without resulting in higher morbidity or mortality.

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Year:  2009        PMID: 19667873     DOI: 10.1097/TA.0b013e3181ac68cf

Source DB:  PubMed          Journal:  J Trauma        ISSN: 0022-5282


  15 in total

Review 1.  Outcome of acute kidney injury in severe burns: a systematic review and meta-analysis.

Authors:  Nele Brusselaers; Stan Monstrey; Kirsten Colpaert; Johan Decruyenaere; Stijn I Blot; Eric A J Hoste
Journal:  Intensive Care Med       Date:  2010-03-24       Impact factor: 17.440

2.  Acute burn resuscitation and fluid creep: it is time for colloid rehabilitation.

Authors:  B S Atiyeh; S A Dibo; A E Ibrahim; E R Zgheib
Journal:  Ann Burns Fire Disasters       Date:  2012-06-30

3.  A case study demonstrating tolerance of the gut to large volumes of enteral fluids as a complement to IV fluid resuscitation in burn shock.

Authors:  Emily W Baird; Colleen M Reid; Leopoldo C Cancio; Jennifer M Gurney; David M Burmeister
Journal:  Int J Burns Trauma       Date:  2021-06-15

4.  Increased expression of cardiac IL-17 after burn.

Authors:  Richard F Oppeltz; Qiong Zhang; Meenakshi Rani; Jennifer R Sasaki; Martin G Schwacha
Journal:  J Inflamm (Lond)       Date:  2010-07-27       Impact factor: 4.981

5.  Abdominal compartment syndrome (ACS) in a severely burned patient.

Authors:  S Kollias; N Stampolidis; P Kourakos; E Mantzari; S Koupidis; S Tsaousi; A Dimitrouli; B Atiyeh; O Castana
Journal:  Ann Burns Fire Disasters       Date:  2015-03-31

6.  A primer on burn resuscitation.

Authors:  Ferdinand K Bacomo; Kevin K Chung
Journal:  J Emerg Trauma Shock       Date:  2011-01

7.  Oxalate Nephropathy After Continuous Infusion of High-Dose Vitamin C as an Adjunct to Burn Resuscitation.

Authors:  Michelle Buehner; Jeremy Pamplin; Lynette Studer; Rhome L Hughes; Booker T King; John C Graybill; Kevin K Chung
Journal:  J Burn Care Res       Date:  2016 Jul-Aug       Impact factor: 1.845

8.  Albumin resuscitation in burns: a hybrid regime to mitigate fluid creep.

Authors:  Judith E Hunter; Peter J Drew; Tom S Potokar; William Dickson; Sarah J Hemington-Gorse
Journal:  Scars Burn Heal       Date:  2016-04-22

9.  Effectiveness of Parkland formula in the estimation of resuscitation fluid volume in adult thermal burns.

Authors:  Geley Ete; Gaurav Chaturvedi; Elvino Barreto; Kingsly Paul M
Journal:  Chin J Traumatol       Date:  2019-03-02

10.  Harborview burns--1974 to 2009.

Authors:  Loren H Engrav; David M Heimbach; Frederick P Rivara; Kathleen F Kerr; Turner Osler; Tam N Pham; Sam R Sharar; Peter C Esselman; Eileen M Bulger; Gretchen J Carrougher; Shari Honari; Nicole S Gibran
Journal:  PLoS One       Date:  2012-07-05       Impact factor: 3.240

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