| Literature DB >> 1966677 |
K Osawa, T Matsumoto, T Maruyama, Y Naito, K Okuda, I Takazoe.
Abstract
Natural materials containing tannin were examined to determine whether they possessed any inhibitory activity against collagenase obtained from the culture supernatant of Bacteroides gingivalis. The collagenolytic activity was determined with Collagenokit CLN-100 (Collagen Technological Co., Tokyo) using FITC-conjugated collagen type 1. Among the test samples, only an aqueous extract of cacao (Theobroma cacao) bean husk strongly inhibited the bacterial collagenase. This inhibitory potency was at the same level as that of tetracycline-HCl.Entities:
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Year: 1990 PMID： 1966677
Source DB: PubMed Journal: Bull Tokyo Dent Coll ISSN： 0040-8891