Literature DB >> 19665963

Alpha cells beget beta cells.

Zhengyu Liu1, Joel F Habener.   

Abstract

Understanding the origins of insulin-producing beta cells of the pancreas could lead to new treatments for diabetes. Collombat et al. (2009) now show that in response to injury, a population of pancreatic progenitor cells can give rise to glucagon-expressing alpha cells that then transdifferentiate into beta cells.

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Year:  2009        PMID: 19665963     DOI: 10.1016/j.cell.2009.07.022

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  7 in total

Review 1.  α-cell role in β-cell generation and regeneration.

Authors:  Joel F Habener; Violeta Stanojevic
Journal:  Islets       Date:  2012 May-Jun       Impact factor: 2.694

2.  Intermittent fasting modulation of the diabetic syndrome in streptozotocin-injected rats.

Authors:  Louiza Belkacemi; Ghalem Selselet-Attou; Emeline Hupkens; Evrard Nguidjoe; Karim Louchami; Abdullah Sener; Willy J Malaisse
Journal:  Int J Endocrinol       Date:  2012-01-12       Impact factor: 3.257

Review 3.  Maintenance of β-cell maturity and plasticity in the adult pancreas: developmental biology concepts in adult physiology.

Authors:  Marta Szabat; Francis C Lynn; Brad G Hoffman; Timothy J Kieffer; Douglas W Allan; James D Johnson
Journal:  Diabetes       Date:  2012-06       Impact factor: 9.461

4.  Lineage conversion of mouse fibroblasts to pancreatic α-cells.

Authors:  Tianjin Liu; Liangliang Sun; Beige Jiang; Limei Li; Jin Cen; Xiaotao Chen; Zhaoyun Zhang; Qinghua Wang; Xin Cheng; Yongquan Shi; Lijian Hui
Journal:  Exp Mol Med       Date:  2017-06-30       Impact factor: 8.718

5.  Cdk4 regulates recruitment of quiescent beta-cells and ductal epithelial progenitors to reconstitute beta-cell mass.

Authors:  Ji-Hyeon Lee; Junghyo Jo; Anandwardhan A Hardikar; Vipul Periwal; Sushil G Rane
Journal:  PLoS One       Date:  2010-01-13       Impact factor: 3.240

6.  β-Cells are not generated in pancreatic duct ligation-induced injury in adult mice.

Authors:  Matthew M Rankin; Christopher J Wilbur; Kimberly Rak; Emily J Shields; Anne Granger; Jake A Kushner
Journal:  Diabetes       Date:  2013-01-24       Impact factor: 9.461

7.  Development and regeneration in the endocrine pancreas.

Authors:  Ahmed Mansouri
Journal:  ISRN Endocrinol       Date:  2012-12-27
  7 in total

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