Literature DB >> 19664700

Biodegradable poly(epsilon-caprolactone)-poly(ethylene glycol) copolymers as drug delivery system.

XiaWei Wei1, ChangYang Gong, MaLing Gou, ShaoZhi Fu, QingFa Guo, Shuai Shi, Feng Luo, Gang Guo, LiYan Qiu, ZhiYong Qian.   

Abstract

Poly(epsilon-caprolactone)-poly(ethylene glycol) (PCL-PEG) copolymers are important synthetic biomedical materials with amphiphilicity, controlled biodegradability, and great biocompatibility. They have great potential application in the fields of nanotechnology, tissue engineering, pharmaceutics, and medicinal chemistry. This review introduced several aspects of PCL-PEG copolymers, including synthetic chemistry, PCL-PEG micro/nanoparticles, PCL-PEG hydrogels, and physicochemical and toxicological properties.

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Year:  2009        PMID： 19664700     DOI： 10.1016/j.ijpharm.2009.07.033

Source DB:  PubMed          Journal:  Int J Pharm        ISSN： 0378-5173            Impact factor:   5.875


  46 in total

1.  Design and evaluation of multifunctional nanocarriers for selective delivery of coenzyme Q10 to mitochondria.

Authors:  Anjali Sharma; Ghareb M Soliman; Noura Al-Hajaj; Rishi Sharma; Dusica Maysinger; Ashok Kakkar
Journal:  Biomacromolecules       Date:  2011-12-16       Impact factor: 6.988

2.  Polymer-controlled release of tobramycin from bone graft void filler.

Authors:  Amanda E Brooks; Benjamin D Brooks; Sherry N Davidoff; Paul C Hogrebe; Mark A Fisher; David W Grainger
Journal:  Drug Deliv Transl Res       Date:  2013-12       Impact factor: 4.617

3.  Quantitative Tissue Spectroscopy of Near Infrared Fluorescent Nanosensor Implants.

Authors:  Nicole M Iverson; Gili Bisker; Edgardo Farias; Vsevolod Ivanov; Jiyoung Ahn; Gerald N Wogan; Michael S Strano
Journal:  J Biomed Nanotechnol       Date:  2016-05       Impact factor: 4.099

4.  Synthesis of PCEC Copolymers with Controlled Molecular Weight Using Full Factorial Methodology.

Authors:  Leila Barghi; Davoud Asgari; Jaleh Barar; Hadi Valizadeh
Journal:  Adv Pharm Bull       Date:  2015-03-05

5.  Goserelin loaded nanoparticles inhibit growth and induce apoptosis in human prostate cancer cell lines.

Authors:  Priti Tomar; Neeti Jain; G S Agarwal; V K Dixit
Journal:  Drug Deliv Transl Res       Date:  2012-08       Impact factor: 4.617

Review 6.  Biomaterials advances in patches for congenital heart defect repair.

Authors:  Seokwon Pok; Jeffrey G Jacot
Journal:  J Cardiovasc Transl Res       Date:  2011-06-07       Impact factor: 4.132

7.  Biodegradable m-PEG/PCL Core-Shell Micelles: Preparation and Characterization as a Sustained Release Formulation for Curcumin.

Authors:  Hossein Danafar; Soodabeh Davaran; Kobra Rostamizadeh; Hadi Valizadeh; Mehrdad Hamidi
Journal:  Adv Pharm Bull       Date:  2014-12-31

8.  Poly(ethylene glycol)-poly(ε-caprolactone) iodinated nanocapsules as contrast agents for X-ray imaging.

Authors:  François Hallouard; Stéphanie Briançon; Nicolas Anton; Xiang Li; Thierry Vandamme; Hatem Fessi
Journal:  Pharm Res       Date:  2013-04-26       Impact factor: 4.200

9.  Investigation of endocytosis and cytotoxicity of poly-d, l-lactide-poly(ethylene glycol) micro/nano-particles in osteoblast cells.

Authors:  Weijia Wang; Shaobing Zhou; Laiyang Guo; Wei Zhi; Xiaohong Li; Jie Weng
Journal:  Int J Nanomedicine       Date:  2010-08-09

10.  Ocular biocompatibility and structural integrity of micro- and nanostructured poly(caprolactone) films.

Authors:  Daniel A Bernards; Robert B Bhisitkul; Paula Wynn; Mark R Steedman; On-Tat Lee; Fergus Wong; Somanus Thoongsuwan; Tejal A Desai
Journal:  J Ocul Pharmacol Ther       Date:  2013-02-07       Impact factor: 2.671
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