Literature DB >> 19662616

Technology and the issue of cost/benefit in diabetes.

Cosimo Giannini1, Angelika Mohn, Francesco Chiarelli.   

Abstract

Diabetes mellitus is the most common endocrine disease in childhood and adolescence. Type 1 diabetes accounts for over 90% of diabetes in children. During the past decades, epidemiological studies have clearly shown a worldwide increase in the incidence of both type 1 and type 2 diabetes in many countries. The worldwide incidence of diabetes and especially the diabetes-related complications highlight the relevant economic burden of this disease. In fact, its costs affect health services, national productivity as well as individuals and families. Hospital in-patient costs for the treatment of complications are the largest single contributor to direct healthcare costs. Anyway, many of these complications and, therefore, their costs, as well as most of the indirect costs, are partially or completely preventable. In fact, intensive therapy, directed at controlling blood glucose, blood pressure and lipid levels, has been shown to be cost effective in that, although initial costs are high, longer term costs decrease as a result of delayed or prevented complications. From this point of view, technological advances have provided new therapeutic options to achieve metabolic control as close to normal as possible in children and adolescents with diabetes. In fact, the relevant technological devices that have been adopted till now, if adequately utilized, should allow patients to achieve intensive management with improved metabolic control, quality of life as well as reduced mortality and morbidity. However, new technologies are not a panacea, and the benefit they provide can be completely achieved only if adequately and especially individually determined. Furthermore, it is inevitable that new modalities of treatment for people with diabetes will be considered critically by healthcare planners and providers in the prevailing global environment of increasing costs of medical care and pressure for rational allocation of resources. Therefore, new technologically derived devices and therapeutic opportunity for diabetes should be rationally utilized in order to offer real advantages and reduce the relevant worldwide cost of diabetes.

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Year:  2009        PMID: 19662616     DOI: 10.1002/dmrr.986

Source DB:  PubMed          Journal:  Diabetes Metab Res Rev        ISSN: 1520-7552            Impact factor:   4.876


  8 in total

1.  Pediatric diabetes registries: when baby steps are not enough.

Authors:  Chad Malone; Gary D Kennedy
Journal:  J Diabetes Sci Technol       Date:  2011-05-01

2.  Uncoupling intensive insulin therapy from weight gain and hypoglycemia in type 1 diabetes.

Authors:  Rebecca J Brown; Rohan C Wijewickrama; David M Harlan; Kristina I Rother
Journal:  Diabetes Technol Ther       Date:  2011-02-28       Impact factor: 6.118

3.  Low-cost production of proinsulin in tobacco and lettuce chloroplasts for injectable or oral delivery of functional insulin and C-peptide.

Authors:  Diane Boyhan; Henry Daniell
Journal:  Plant Biotechnol J       Date:  2010-12-08       Impact factor: 9.803

4.  Oral delivery of therapeutic proteins bioencapsulated in plant cells: preclinical and clinical advances.

Authors:  Imran Khan; Henry Daniell
Journal:  Curr Opin Colloid Interface Sci       Date:  2021-03-24       Impact factor: 8.209

5.  Pediatric Type 1 Diabetes: Reducing Admission Rates for Diabetes Ketoacidosis.

Authors:  Jeniece Trast Ilkowitz; Steven Choi; Michael L Rinke; Kathy Vandervoot; Rubina A Heptulla
Journal:  Qual Manag Health Care       Date:  2016 Oct/Dec       Impact factor: 0.926

6.  Cost-effectiveness of financial incentives to improve glycemic control in adults with diabetes: A pilot randomized controlled trial.

Authors:  Leonard E Egede; Rebekah J Walker; Clara E Dismuke-Greer; Sarah Pyzyk; Aprill Z Dawson; Joni S Williams; Jennifer A Campbell
Journal:  PLoS One       Date:  2021-03-18       Impact factor: 3.240

7.  Human αB-crystallin as fusion protein and molecular chaperone increases the expression and folding efficiency of recombinant insulin.

Authors:  Mohsen Akbarian; Reza Yousefi
Journal:  PLoS One       Date:  2018-10-19       Impact factor: 3.240

8.  Cost-Effectiveness of Technology-Assisted Case Management in Low-Income, Rural Adults with Type 2 Diabetes.

Authors:  Leonard E Egede; Clara E Dismuke; Rebekah J Walker; Joni S Williams; Christian Eiler
Journal:  Health Equity       Date:  2021-07-26
  8 in total

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