Literature DB >> 19662568

Effect of bergapten from Heracleum nepalense root on production of proinflammatory cytokines.

Sekhar K Bose1, Saikat Dewanjee, Ranabir Sahu, Sankar P Dey.   

Abstract

In the present investigation, the anti-inflammatory activity of isolated bergapten from hydroalcoholic extract of Heracleum nepalense root was evaluated in vitro using human peripheral blood mononuclear cells (PBMCs). Bergapten exhibited significant inhibition of the production of pro-inflammatory cytokines, namely tumour necrotic factor-α (TNF-α) and interleukin-6 (IL-6) by PBMCs stimulated with lipopolysaccharide in a concentration-dependent manner.

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Year:  2011        PMID： 19662568     DOI： 10.1080/14786410902800665

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  10 in total

1.  Bergapten promotes bone marrow stromal cell differentiation into osteoblasts in vitro and in vivo.

Authors:  Ji-jie Xiao; Wen-ji Zhao; Xin-tao Zhang; Wen-long Zhao; Xiao-xia Wang; Shu-hui Yin; Fang Jiang; Yin-xia Zhao; Fang-ni Chen; Shao-lin Li
Journal:  Mol Cell Biochem       Date:  2015-07-19       Impact factor: 3.396

2.  Protective effects of 5-methoxypsoralen against acetaminophen-induced hepatotoxicity in mice.

Authors:  Wei-Xia Liu; Feng-Lan Jia; Yue-Ying He; Bao-Xu Zhang
Journal:  World J Gastroenterol       Date:  2012-05-14       Impact factor: 5.742

3.  Bergapten inhibits chemically induced nociceptive behavior and inflammation in mice by decreasing the expression of spinal PARP, iNOS, COX-2 and inflammatory cytokines.

Authors:  Gurjit Singh; Anudeep Kaur; Jashanpreet Kaur; Manpreet S Bhatti; Palwinder Singh; Rajbir Bhatti
Journal:  Inflammopharmacology       Date:  2019-04-05       Impact factor: 4.473

Review 4.  Pharmacological Properties of Bergapten: Mechanistic and Therapeutic Aspects.

Authors:  Maria Magdalena Quetglas-Llabrés; Cristina Quispe; Jesús Herrera-Bravo; Marcelo D Catarino; Olívia R Pereira; Susana M Cardoso; Kamal Dua; Dinesh Kumar Chellappan; Kavita Pabreja; Saurabh Satija; Meenu Mehta; Antoni Sureda; Miquel Martorell; Dinara Satmbekova; Balakyz Yeskaliyeva; Javad Sharifi-Rad; Naeem Rasool; Monica Butnariu; Iulia Cristina Bagiu; Radu Vasile Bagiu; Daniela Calina; William C Cho
Journal:  Oxid Med Cell Longev       Date:  2022-04-25       Impact factor: 7.310

5.  Bergapten prevents lipopolysaccharide mediated osteoclast formation, bone resorption and osteoclast survival.

Authors:  Mingxia Zheng; Yongliang Ge; Haiyu Li; Ming Yan; Jin Zhou; Yun Zhang
Journal:  Int Orthop       Date:  2013-12-04       Impact factor: 3.075

Review 6.  Natural source, bioactivity and synthesis of benzofuran derivatives.

Authors:  Yu-Hang Miao; Yu-Heng Hu; Jie Yang; Teng Liu; Jie Sun; Xiao-Jing Wang
Journal:  RSC Adv       Date:  2019-09-02       Impact factor: 4.036

7.  Allergic Airway-Induced Hypersensitivity Is Attenuated by Bergapten in Murine Models of Inflammation.

Authors:  Douglas B Aidoo; David D Obiri; Newman Osafo; Aaron O Antwi; Leslie B Essel; Babatunde M Duduyemi; Martins Ekor
Journal:  Adv Pharmacol Sci       Date:  2019-02-03

8.  Bergapten alleviates osteoarthritis by regulating the ANP32A/ATM signaling pathway.

Authors:  Yi He; Zeng Zisan; Zhenhui Lu; Li Zheng; Jinmin Zhao
Journal:  FEBS Open Bio       Date:  2019-05-23       Impact factor: 2.693

9.  Protective Effect of Bergapten against Human Erythrocyte Hemolysis and Protein Denaturation In Vitro.

Authors:  Douglas Bosco Aidoo; Daniels Konja; Isaac Tabiri Henneh; Martins Ekor
Journal:  Int J Inflam       Date:  2021-12-21

10.  Metabolomic Analysis, Fast Isolation of Phenolic Compounds, and Evaluation of Biological Activities of the Bark From Weinmannia trichosperma Cav. (Cunoniaceae).

Authors:  Ruth Barrientos; Carlos Fernández-Galleguillos; Edgar Pastene; Mario Simirgiotis; Javier Romero-Parra; Shakeel Ahmed; Javier Echeverría
Journal:  Front Pharmacol       Date:  2020-05-27       Impact factor: 5.810
  10 in total

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