Literature DB >> 19662054

Is there a role for triclosan/copolymer toothpaste in the management of periodontal disease?

Anthony Blinkhorn1, P M Bartold, M P Cullinan, T E Madden, R I Marshall, S L Raphael, G J Seymour.   

Abstract

Dental caries and periodontal disease are the most common oral conditions experienced by adults today. The treatment of these diseases by the dental team can only be performed when patients attend dental practices. There is recognition that the preventive measures patients perform at home between dental visits is of vital importance in the control of these diseases. Water fluoridation and fluoridated toothpastes have made enormous progress into the prevention of dental caries worldwide. However, prevention of periodontal disease is yet to enjoy the same success. A number of toothpastes have been developed for the prevention and control of periodontal disease. One such toothpaste - containing triclosan/copolymer - has been thoroughly researched. The literature pertaining to the efficacy, mode of action and safety of triclosan/copolymer toothpaste has been reviewed. A MEDLINE search identified 198 articles dated from 1989 to 2008. The findings of this body of research are discussed and conclusions regarding the efficacy of triclosan/copolymer toothpaste in the home-care management of periodontal disease are presented.

Entities:  

Mesh:

Substances:

Year:  2009        PMID: 19662054     DOI: 10.1038/sj.bdj.2009.669

Source DB:  PubMed          Journal:  Br Dent J        ISSN: 0007-0610            Impact factor:   1.626


  14 in total

1.  Using DGGE and 16S rRNA gene sequence analysis to evaluate changes in oral bacterial composition.

Authors:  Zhou Chen; Harsh M Trivedi; Nok Chhun; Virginia M Barnes; Deepak Saxena; Tao Xu; Yihong Li
Journal:  Chin J Dent Res       Date:  2011

2.  Structural characterization of Porphyromonas gingivalis enoyl-ACP reductase II (FabK).

Authors:  Kirk E Hevener; Bernard D Santarsiero; Hyun Lee; Jesse A Jones; Teuta Boci; Michael E Johnson; Shahila Mehboob
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2018-01-26       Impact factor: 1.056

3.  Triclosan produces statistically significant reduction in plaque, gingivitis and caries but not clinically important benefit.

Authors:  Ferne Kraglund
Journal:  Evid Based Dent       Date:  2014-03

4.  Expression, purification and characterization of enoyl-ACP reductase II, FabK, from Porphyromonas gingivalis.

Authors:  Kirk E Hevener; Shahila Mehboob; Teuta Boci; Kent Truong; Bernard D Santarsiero; Michael E Johnson
Journal:  Protein Expr Purif       Date:  2012-07-20       Impact factor: 1.650

5.  Type 1 diabetes-associated TLR responsiveness of oral epithelial cells.

Authors:  K G Neiva; N L Calderon; T R Alonso; F Panagakos; S M Wallet
Journal:  J Dent Res       Date:  2013-12-13       Impact factor: 6.116

6.  Inhibitory effects of children's toothpastes on Streptococcus mutans, Streptococcus sanguinis and Lactobacillus acidophilus.

Authors:  A Evans; S J Leishman; L J Walsh; W K Seow
Journal:  Eur Arch Paediatr Dent       Date:  2014-11-18

7.  Spontaneously Arising Streptococcus mutans Variants with Reduced Susceptibility to Chlorhexidine Display Genetic Defects and Diminished Fitness.

Authors:  Justin R Kaspar; Matthew J Godwin; Irina M Velsko; Vincent P Richards; Robert A Burne
Journal:  Antimicrob Agents Chemother       Date:  2019-06-24       Impact factor: 5.191

8.  MyD88-mediated innate sensing by oral epithelial cells controls periodontal inflammation.

Authors:  Andrea E Delitto; Fernanda Rocha; Ann M Decker; Byron Amador; Heather L Sorenson; Shannon M Wallet
Journal:  Arch Oral Biol       Date:  2017-12-16       Impact factor: 2.633

Review 9.  Triclosan/copolymer containing toothpastes for oral health.

Authors:  Philip Riley; Thomas Lamont
Journal:  Cochrane Database Syst Rev       Date:  2013-12-05

10.  Triclosan alters antimicrobial and inflammatory responses of epithelial cells.

Authors:  M A Wallet; N l Calderon; T R Alonso; C S Choe; D l Catalfamo; C J Lalane; K G Neiva; F Panagakos; S M Wallet
Journal:  Oral Dis       Date:  2013-04       Impact factor: 3.511

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.