| Literature DB >> 19661689 |
Yuya Kawaguchi1, Satoshi Yamauchi, Kenta Masuda, Hisashi Nishiwaki, Koichi Akiyama, Masafumi Maruyama, Takuya Sugahara, Taro Kishida, Yojiro Koba.
Abstract
The relationship between the stereochemistry and antimicrobial activity of butane-type lignans was clarified. All stereoisomers of dihydroguaiaretic acid (DGA) showed both antibacterial and antifungal activity. The (+)- and (-)-7,7'-dioxodihydroguaiaretic acid (ODGA) also showed both antibacterial and antifungal activity, while meso-ODGA did not show antibacterial activity, but showed antifungal activity. No activity of any stereoisomer of secoisolariciresinol (SECO) was apparent.Entities:
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Year: 2009 PMID： 19661689 DOI： 10.1271/bbb.90167
Source DB: PubMed Journal: Biosci Biotechnol Biochem ISSN： 0916-8451 Impact factor: 2.043