Literature DB >> 19660373

Effects and mechanisms of left ventricular false tendons on functional mitral regurgitation in patients with severe cardiomyopathy.

Mehul R Bhatt1, Carlos E Alfonso, Amar M Bhatt, Sangmin Lee, Alexandre C Ferreira, Tomas A Salerno, Eduardo de Marchena.   

Abstract

OBJECTIVE: False tendons in the left ventricle are commonly observed. Preliminary observations associate false tendons with less functional mitral regurgitation.
METHODS: Echocardiograms demonstrating severe cardiomyopathy (ejection fraction < or =30%) were retrospectively examined for left ventricular false tendons. The ejection fraction, cause of left ventricular systolic dysfunction, left ventricular diastolic dimensions, severity of mitral regurgitation, mitral annular diameter, mitral valve coaptation depth, mitral valve coaptation area, and orientation of false tendon were evaluated. The patients with false tendons were compared with a control group with cardiomyopathy without false tendons.
RESULTS: A cohort of patients (n = 82) with severe left ventricular systolic dysfunction (mean ejection fraction, 21%) and false tendons were compared with a control group with similar left ventricular dysfunction and no false tendons (n = 121; mean ejection fraction, 20%; P = .10). The patients with false tendons had similar left ventricular diastolic internal dimensions compared with the control group (5.99 and 6.18 cm, respectively; P = .086). Yet patients with false tendons had a very low incidence of severe functional mitral regurgitation compared with the control group (4.9% vs 27%, P < .001). Patients with false tendons had significantly smaller mitral annular diameters (3.57 vs 4.03 cm, P < .001), shorter mitral valve coaptation depths (0.89 vs 1.24 cm, P < .001), and reduced coaptation areas (1.61 vs 2.52 cm(2), P < .001) than the control group. The reduction of mitral regurgitation was more significant for patient with transverse midcavity false tendons.
CONCLUSIONS: Patients with false tendons and cardiomyopathy have less severe mitral regurgitation. The mechanism for the reduction in functional mitral regurgitation might be less mitral valve deformation, specifically lower coaptation depth and coaptation area when a false tendon is present.

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Year:  2009        PMID: 19660373     DOI: 10.1016/j.jtcvs.2008.10.056

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  5 in total

1.  The violin heart.

Authors:  James Ker
Journal:  Clin Med Insights Cardiol       Date:  2010-07-20

2.  Left intraventricular dyssynchrony caused by a false tendon.

Authors:  Tadanobu Irie; Koji Kurosawa; Yoshiaki Kaneko; Tadashi Nakajima; Rieko Tateno; Masahiko Kurabayashi
Journal:  J Arrhythm       Date:  2014-10-23

3.  Protective Role of False Tendon in Subjects with Left Bundle Branch Block: A Virtual Population Study.

Authors:  Matthias Lange; Luigi Yuri Di Marco; Karim Lekadir; Toni Lassila; Alejandro F Frangi
Journal:  PLoS One       Date:  2016-01-14       Impact factor: 3.240

4.  Left ventricular false tendon in a patient undergoing mitral valve replacement.

Authors:  S Subash; Parimala Prasanna Simha; Amarja Nagre; Balaji Babu; A M Jagadeesh
Journal:  Ann Card Anaesth       Date:  2015 Jan-Mar

5.  Three-dimensional echocardiographic assessment of Chiari's network relationship with the left ventricular false tendon.

Authors:  Mutlu Cagan Sumerkan; Sukru Cetin; Fusun Behramoglu Helvaci; Sendag Satilmis Yaslikaya; Umut Karabay; Turgun Hamit; Ahmet Gurdal; Mehmet Agirbasli; Omer Alyan
Journal:  Egypt Heart J       Date:  2022-06-15
  5 in total

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