Literature DB >> 19658171

Genetic and environmental influences on restrained eating behavior.

Ellen Schur1, Carolyn Noonan, Janet Polivy, Jack Goldberg, Dedra Buchwald.   

Abstract

OBJECTIVE: We examined the relative contributions of genetic and environmental influences to restrained eating.
METHOD: Restrained eating was assessed by the Restraint Scale in a survey mailed to all twins enrolled in the University of Washington Twin Registry. We used structural equation modeling to estimate genetic and nongenetic contributions to restrained eating.
RESULTS: 1,196 monozygotic (MZ), 456 same-sex dizygotic (DZ) twins, and 447 opposite-sex twins were included in analyses. Restraint Scale scores were more closely correlated in MZ twins (r(male) = .55, r(female) = .55) than in same-sex DZ twins (r(male) = .31, r(female) = .19). Based on structural equation modeling, the estimated heritability for restrained eating, adjusted for body mass index (BMI) and sex, was 43% (95% confidence interval 35-50%). There was little evidence for common environmental effects. DISCUSSION: These results indicate an inherited component to restrained eating. Genes could influence restrained eating directly or through inherited mediators such as personality factors or tendencies to gain weight.

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Year:  2009        PMID: 19658171      PMCID: PMC2784007          DOI: 10.1002/eat.20734

Source DB:  PubMed          Journal:  Int J Eat Disord        ISSN: 0276-3478            Impact factor:   4.861


  46 in total

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6.  Neuroticism and introversion: a risky combination for disordered eating among a non-clinical sample of undergraduate women.

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10.  Familial resemblance in eating behaviors in men and women from the Quebec Family Study.

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1.  Brain regulation of appetite in twins.

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2.  Acquired differences in brain responses among monozygotic twins discordant for restrained eating.

Authors:  Ellen A Schur; Natalia M Kleinhans; Jack Goldberg; Dedra S Buchwald; Janet Polivy; Angelo Del Parigi; Kenneth R Maravilla
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3.  FTO genotype impacts food intake and corticolimbic activation.

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4.  The association of restrained eating with weight change over time in a community-based sample of twins.

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Review 5.  The heritability of eating disorders: methods and current findings.

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6.  A twin study of differences in the response of plasma ghrelin to a milkshake preload in restrained eaters.

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Review 7.  What Twin Studies Tell Us About Brain Responses to Food Cues.

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8.  Genetic and environmental influences on posttraumatic stress disorder symptoms and disinhibited eating behaviors.

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9.  Negative affect mediates effects of psychological stress on disordered eating in young Chinese women.

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10.  Reassessing relationships between appetite and adiposity in people at risk of obesity: A twin study using fMRI.

Authors:  Leticia E Sewaybricker; Susan J Melhorn; Jennifer L Rosenbaum; Mary K Askren; Vidhi Tyagi; Mary F Webb; Mary Rosalynn B De Leon; Thomas J Grabowski; Ellen A Schur
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