Literature DB >> 19655099

The use of disulfiram for alcohol-dependent patients and duration of outpatient treatment.

Márcia Fonsi Elbreder1, Dorisdaia Carvalho de Humerez, Ronaldo Laranjeira.   

Abstract

Despite the fact that alcoholism is a severe public health problem of worldwide proportions, only a limited number of medications is used as coadjuvant treatment. The objectives of this study were to analyse the use of disulfiram for alcohol-dependent patients and the immediate interruption of treatment following medication prescription. This is a transversal study of 810 patients who attended the Alcohol and Drug Research Unit (UNIAD) during the 2000-2006 period. The study showed that both male and female patients who had remained under treatment during the first year used proportionally more disulfiram than those who remained for lesser time under treatment, and immediate treatment interruption was statistically more significant in this latter group of patients after prescription of this medication. Although disulfiram is an old medication, it seems that this drug can be useful for keeping alcohol-dependent patients under outpatient treatment.

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Year:  2009        PMID: 19655099     DOI: 10.1007/s00406-009-0038-9

Source DB:  PubMed          Journal:  Eur Arch Psychiatry Clin Neurosci        ISSN: 0940-1334            Impact factor:   5.270


  23 in total

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Journal:  Addiction       Date:  2005-11       Impact factor: 6.526

4.  The role of the early therapeutic alliance in predicting drug treatment dropout.

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Authors:  Christopher J Armitage
Journal:  Br J Health Psychol       Date:  2008-10-14

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Authors:  F GELBMAN; N B EPSTEIN
Journal:  Can Med Assoc J       Date:  1949-06       Impact factor: 8.262

7.  Disulfiram implants: the right treatment but the wrong drug?

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Journal:  Can Med Assoc J       Date:  1977-06-18       Impact factor: 8.262

8.  [Epidemiology of alcohol use in Brazil].

Authors:  José Carlos F Galduróz; Raul Caetano
Journal:  Braz J Psychiatry       Date:  2005-01-04       Impact factor: 2.697

9.  Five years of alcohol de-addiction services in a tertiary care general hospital.

Authors:  R Chandrasekaran; B Sivaprakash; V Chitraleka
Journal:  Indian J Psychiatry       Date:  2001-01       Impact factor: 1.759

10.  Does psychiatric comorbidity in alcohol-dependent patients affect treatment outcome?

Authors:  Karl Mann; Thomas Hintz; Martin Jung
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2004-06       Impact factor: 5.270

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  1 in total

1.  Long-term γ-hydroxybutyric acid (GHB) and disulfiram combination therapy in GHB treatment-resistant chronic alcoholics.

Authors:  Angelo Giovanni Icro Maremmani; Pier Paolo Pani; Luca Rovai; Matteo Pacini; Liliana Dell'Osso; Icro Maremmani
Journal:  Int J Environ Res Public Health       Date:  2011-07-06       Impact factor: 3.390

  1 in total

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