Literature DB >> 19655029

A low-cost, linear, DC - 35 MHz, high-power LED driver for continuous wave (CW) and fluorescence lifetime imaging (FLIM).

Sylvain Gioux1, Vida Kianzad, Razvan Ciocan, Hak Soo Choi, Chad Nelson, Jeffrey Thumm, Robert J Filkins, Stephen J Lomnes, John V Frangioni.   

Abstract

Near-infrared (NIR) fluorescence has the potential to provide surgeons with real-time intraoperative image-guidance. Increasing the signal-to-background ratio of fluorescent agents involves delivering a controllable excitation fluence rate of proper wavelength and/or using complementary imaging techniques such as FLIM. In this study we describe a low-cost linear driver circuit capable of driving Light Emitting Diodes (LEDs) from DC to 35 MHz, at high power, and which permit fluorescence CW and lifetime measurements. The electronic circuit Gerber files described in this article and the list of components are available online at www.frangionilab.org.

Entities:  

Year:  2008        PMID： 19655029      PMCID： PMC2719859          DOI： 10.1117/12.779196

Source DB:  PubMed          Journal:  Proc SPIE Int Soc Opt Eng        ISSN： 0277-786X


  8 in total

Review 1.  Fluorescence-enhanced, near infrared diagnostic imaging with contrast agents.

Authors:  Eva M Sevick-Muraca; Jessica P Houston; Michael Gurfinkel
Journal:  Curr Opin Chem Biol       Date:  2002-10       Impact factor: 8.822

Review 2.  Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging.

Authors:  Vasilis Ntziachristos; Christoph Bremer; Ralph Weissleder
Journal:  Eur Radiol       Date:  2002-07-19       Impact factor: 5.315

3.  High-affinity near-infrared fluorescent small-molecule contrast agents for in vivo imaging of prostate-specific membrane antigen.

Authors:  Valerie Humblet; Rena Lapidus; Larry R Williams; Takashi Tsukamoto; Camilo Rojas; Pavel Majer; Bunda Hin; Shunsuke Ohnishi; Alec M De Grand; Atif Zaheer; Jürgen T Renze; Akira Nakayama; Barbara S Slusher; John V Frangioni
Journal:  Mol Imaging       Date:  2005 Oct-Dec       Impact factor: 4.488

4.  Image-guided oncologic surgery using invisible light: completed pre-clinical development for sentinel lymph node mapping.

Authors:  Eiichi Tanaka; Hak Soo Choi; Hirofumi Fujii; Moungi G Bawendi; John V Frangioni
Journal:  Ann Surg Oncol       Date:  2006-09-29       Impact factor: 5.344

5.  Real-time intraoperative ureteral guidance using invisible near-infrared fluorescence.

Authors:  Eiichi Tanaka; Shunsuke Ohnishi; Rita G Laurence; Hak Soo Choi; Valerie Humblet; John V Frangioni
Journal:  J Urol       Date:  2007-09-17       Impact factor: 7.450

6.  Image-guided quantification of cardioplegia delivery during cardiac surgery.

Authors:  Edward G Soltesz; Rita G Laurence; Alec M De Grand; Lawrence H Cohn; Tomislav Mihaljevic; John V Frangioni
Journal:  Heart Surg Forum       Date:  2007       Impact factor: 0.676

7.  Near-infrared fluorescence imaging of microcalcification in an animal model of breast cancer.

Authors:  Robert E Lenkinski; Muneeb Ahmed; Atif Zaheer; John V Frangioni; S Nahum Goldberg
Journal:  Acad Radiol       Date:  2003-10       Impact factor: 3.173

8.  An operational near-infrared fluorescence imaging system prototype for large animal surgery.

Authors:  A M De Grand; J V Frangioni
Journal:  Technol Cancer Res Treat       Date:  2003-12
  8 in total
  4 in total

1.  Low-frequency wide-field fluorescence lifetime imaging using a high-power near-infrared light-emitting diode light source.

Authors:  Sylvain Gioux; Stephen J Lomnes; Hak Soo Choi; John V Frangioni
Journal:  J Biomed Opt       Date:  2010 Mar-Apr       Impact factor: 3.170

2.  Optimization of fluorescent imaging in the operating room through pulsed acquisition and gating to ambient background cycling.

Authors:  Kristian J Sexton; Yan Zhao; Scott C Davis; Shudong Jiang; Brian W Pogue
Journal:  Biomed Opt Express       Date:  2017-04-26       Impact factor: 3.732

3.  High-power, computer-controlled, light-emitting diode-based light sources for fluorescence imaging and image-guided surgery.

Authors:  Sylvain Gioux; Vida Kianzad; Razvan Ciocan; Sunil Gupta; Rafiou Oketokoun; John V Frangioni
Journal:  Mol Imaging       Date:  2009 May-Jun       Impact factor: 4.488

4.  Intraoperative biophotonic imaging systems for image-guided interventions.

Authors:  Salar Sajedi; Hamid Sabet; Hak Soo Choi
Journal:  Nanophotonics       Date:  2018-12-14       Impact factor: 8.449
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.