Literature DB >> 19650125

Propranolol for airway hemangiomas: case report of novel treatment.

Lisa Buckmiller1, Umesh Dyamenahalli, Gresham T Richter.   

Abstract

Infantile hemangiomas arising in the trachea are rare. These lesions pose a management dilemma as several treatment options can provide safe management. Propranolol, a nonselective beta-blocker, has recently been introduced as a novel modality for the treatment of proliferating hemangiomas. This report illustrates the successful management of tracheal hemangiomas using oral propranolol in a young patient with otherwise treatment-resistant airway lesions. Despite various endoscopic therapeutic attempts, the patient remained stridulous with airway disease that persisted into the involution phase of the average hemangioma cycle. Within 6 weeks of beginning oral propranolol (2 mg/kg/day), her airway compromise was eliminated and she had complete resolution of endoscopically visible disease. No side effects from propranolol occurred. We propose that oral propranolol should be considered for use in airway hemangiomas.

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Year:  2009        PMID: 19650125     DOI: 10.1002/lary.20633

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  21 in total

1.  Use of propranolol in infantile haemangiomas: report of five cases and review of the literature.

Authors:  D Gidaris; M Economou; V Hatzidemetriou; N Gombakis; M Athanassiou-Metaxa
Journal:  Hippokratia       Date:  2011-01       Impact factor: 0.471

Review 2.  [Current aspects of eyelid, lacrimal and orbital surgery in childhood].

Authors:  G Avgitidou; K R Koch; C Cursiefen; L M Heindl
Journal:  Ophthalmologe       Date:  2015-02       Impact factor: 1.059

Review 3.  Efficacy and adverse effects of oral propranolol in infantile hemangioma: a meta-analysis of comparative studies.

Authors:  Hao Yang; Dong-Lai Hu; Qiang Shu; Xiao-Dong Guo
Journal:  World J Pediatr       Date:  2019-07-24       Impact factor: 2.764

4.  Dramatic shift in the infantile hemangioma treatment paradigm at a single institution.

Authors:  Jennifer Gomulka; Dawn H Siegel; Beth A Drolet
Journal:  Pediatr Dermatol       Date:  2013-10-11       Impact factor: 1.588

5.  Ultrasound and colour Doppler in infantile subglottic haemangioma.

Authors:  Leo Rossler; T Rothoeft; N Teig; C Koerner-Rettberg; T Deitmer; C H L Rieger; E Hamelmann
Journal:  Pediatr Radiol       Date:  2011-09-09

6.  The expression of renin-angiotensin-aldosterone axis components in infantile hemangioma tissue and the impact of propranolol treatment.

Authors:  James R Dornhoffer; Ting Wei; Haihong Zhang; Emily Miller; Mario A Cleves; Gresham T Richter
Journal:  Pediatr Res       Date:  2017-05-03       Impact factor: 3.756

Review 7.  Management of infantile hemangiomas : current and potential pharmacotherapeutic approaches.

Authors:  Brittany G Craiglow; Richard J Antaya
Journal:  Paediatr Drugs       Date:  2013-04       Impact factor: 3.022

8.  Periocular capillary hemangiomas: indications and options for treatment.

Authors:  Genie M Bang; Pete Setabutr
Journal:  Middle East Afr J Ophthalmol       Date:  2010-04

9.  Developing a Nanoparticle-Delivered High-Efficacy Treatment for Infantile Hemangiomas Using a Mouse Hemangioendothelioma Model.

Authors:  Hakan Orbay; Yuanpei Li; Wenwu Xiao; Simon R Cherry; Kit Lam; David E Sahar
Journal:  Plast Reconstr Surg       Date:  2016-08       Impact factor: 4.730

Review 10.  The changing face of complicated infantile hemangioma treatment.

Authors:  Deanna Menapace; Mario Mitkov; Richard Towbin; Marcia Hogeling
Journal:  Pediatr Radiol       Date:  2016-07-23
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