Literature DB >> 1964942

Blood donor screening for parvovirus B19.

B J Cohen1, A M Field, S Gudnadottir, S Beard, J A Barbara.   

Abstract

A programme of blood donor screening for parvovirus B19 was conducted from January to May 1990. The main aim of the study was to identify a B19 positive donation that could be used as a source of viral antigen for diagnostic serology. Out of 24,000 donors tested one was positive for B19 antigen by counter current immunoelectrophoresis and over 100 ml of undiluted B19 containing material was obtained. However, much of the positive donation was incorporated in a plasma pool of 28 donations. An acid dissociation technique was used to recover B19 antigen from immune complexes formed in the plasma pool.

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Year:  1990        PMID: 1964942     DOI: 10.1016/0166-0934(90)90065-n

Source DB:  PubMed          Journal:  J Virol Methods        ISSN: 0166-0934            Impact factor:   2.014


  3 in total

1.  Two anti-parvovirus B 19 IgM capture assays incorporating a mouse monoclonal antibody specific for B 19 viral capsid proteins VP 1 and VP 2.

Authors:  H J O'Neill; P V Coyle
Journal:  Arch Virol       Date:  1992       Impact factor: 2.574

2.  Sequence analysis of a parvovirus B19 isolate and baculovirus expression of the non-structural protein.

Authors:  K E Hicks; R C Cubel; B J Cohen; J P Clewley
Journal:  Arch Virol       Date:  1996       Impact factor: 2.574

3.  Detection of parvovirus B19 in donated blood: a model system for screening by polymerase chain reaction.

Authors:  F McOmish; P L Yap; A Jordan; H Hart; B J Cohen; P Simmonds
Journal:  J Clin Microbiol       Date:  1993-02       Impact factor: 5.948

  3 in total

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