Literature DB >> 19648940

Osteoimmunology: Wnt antagonists: for better or worse?

Rik J Lories1, Frank P Luyten.   

Abstract

Molecules involved in developmental signaling pathways have emerged as therapeutic targets for various rheumatic diseases. New research sheds light on the consequences of interfering with these processes.

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Year:  2009        PMID: 19648940     DOI: 10.1038/nrrheum.2009.144

Source DB:  PubMed          Journal:  Nat Rev Rheumatol        ISSN: 1759-4790            Impact factor:   20.543


  9 in total

Review 1.  Contemporary concepts of inflammation, damage and repair in rheumatic diseases.

Authors:  Frank P Luyten; Rik J U Lories; Patrick Verschueren; Kurt de Vlam; René Westhovens
Journal:  Best Pract Res Clin Rheumatol       Date:  2006-10       Impact factor: 4.098

Review 2.  Mechanisms of anabolic therapies for osteoporosis.

Authors:  Ernesto Canalis; Andrea Giustina; John P Bilezikian
Journal:  N Engl J Med       Date:  2007-08-30       Impact factor: 91.245

Review 3.  The role of Wnt proteins in arthritis.

Authors:  Georg Schett; Jochen Zwerina; Jean-Pierre David
Journal:  Nat Clin Pract Rheumatol       Date:  2008-09

4.  Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis.

Authors:  Rik J U Lories; Inge Derese; Frank P Luyten
Journal:  J Clin Invest       Date:  2005-05-12       Impact factor: 14.808

5.  Dickkopf-1 is a master regulator of joint remodeling.

Authors:  Danielle Diarra; Marina Stolina; Karin Polzer; Jochen Zwerina; Michael S Ominsky; Denise Dwyer; Adelheid Korb; Josef Smolen; Markus Hoffmann; Clemens Scheinecker; Desiree van der Heide; Robert Landewe; Dave Lacey; William G Richards; Georg Schett
Journal:  Nat Med       Date:  2007-01-21       Impact factor: 53.440

Review 6.  Wnt signaling and osteoarthritis.

Authors:  Frank P Luyten; Przemko Tylzanowski; Rik J Lories
Journal:  Bone       Date:  2008-12-14       Impact factor: 4.398

7.  Radiographic progression of ankylosing spondylitis after up to two years of treatment with etanercept.

Authors:  D van der Heijde; R Landewé; S Einstein; P Ory; D Vosse; L Ni; S-L Lin; W Tsuji; J C Davis
Journal:  Arthritis Rheum       Date:  2008-05

8.  Blockade of Dickkopf (DKK)-1 induces fusion of sacroiliac joints.

Authors:  S Uderhardt; D Diarra; J Katzenbeisser; J-P David; J Zwerina; W Richards; G Kronke; G Schett
Journal:  Ann Rheum Dis       Date:  2009-03-19       Impact factor: 19.103

9.  Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice.

Authors:  Maya Kansara; Michael Tsang; Laurent Kodjabachian; Natalie A Sims; Melanie K Trivett; Mathias Ehrich; Alexander Dobrovic; John Slavin; Peter F M Choong; Paul J Simmons; Igor B Dawid; David M Thomas
Journal:  J Clin Invest       Date:  2009-03-23       Impact factor: 14.808

  9 in total
  4 in total

Review 1.  The balance of tissue repair and remodeling in chronic arthritis.

Authors:  Rik Lories
Journal:  Nat Rev Rheumatol       Date:  2011-10-18       Impact factor: 20.543

Review 2.  Can bone loss in rheumatoid arthritis be prevented?

Authors:  M Vis; M Güler-Yüksel; W F Lems
Journal:  Osteoporos Int       Date:  2013-06-18       Impact factor: 4.507

Review 3.  Inflammatory rheumatic disorders and bone.

Authors:  Irene E M Bultink; Marijn Vis; Irene E van der Horst-Bruinsma; Willem F Lems
Journal:  Curr Rheumatol Rep       Date:  2012-06       Impact factor: 4.592

Review 4.  Osteoimmunology and Beyond.

Authors:  Lia Ginaldi; Massimo De Martinis
Journal:  Curr Med Chem       Date:  2016       Impact factor: 4.530

  4 in total

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