Literature DB >> 19647711

Validation issues around DNA typing of low level DNA.

John Buckleton1.   

Abstract

A recent ruling in the Crown Court of Northern Ireland, R v. Hoey, [R v Sean Hoey. 2007, Crown Court of Northern Ireland] has raised questions about the validity of one variant of DNA analysis, often termed LCN. The ruling and subsequent discussion also raises questions about what constitutes validation of a technique. This paper examines what can be achieved in a laboratory based validation study against the Daubert standard and against guidance given in the UK. There is a significant discrepancy between what can be achieved and the Daubert standard but much less of a discrepancy against the UK guidance. Much of the difference relates to differences in word usage, definitional difficulties, and a lack of mutual understanding and communication between the judiciary and forensic scientists. This highlights a gap that needs attention.

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Year:  2009        PMID: 19647711     DOI: 10.1016/j.fsigen.2009.04.003

Source DB:  PubMed          Journal:  Forensic Sci Int Genet        ISSN: 1872-4973            Impact factor:   4.882


  2 in total

Review 1.  Back to the Future - Part 2. Post-mortem assessment and evolutionary role of the bio-medicolegal sciences.

Authors:  Santo Davide Ferrara; Giovanni Cecchetto; Rossana Cecchi; Donata Favretto; Silke Grabherr; Takaki Ishikawa; Toshikazu Kondo; Massimo Montisci; Heidi Pfeiffer; Maurizio Rippa Bonati; Dina Shokry; Marielle Vennemann; Thomas Bajanowski
Journal:  Int J Legal Med       Date:  2017-04-25       Impact factor: 2.686

2.  Comparison of STR profiling from low template DNA extracts with and without the consensus profiling method.

Authors:  Kelly S Grisedale; Angela van Daal
Journal:  Investig Genet       Date:  2012-07-02
  2 in total

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