Literature DB >> 19647215

Metastasis-promoting immunity: when T cells turn to the dark side.

Drew Pardoll1.   

Abstract

While the role of endogenous T cells in antitumor immunity is being debated, little is known about whether and how T cells promote tumorigenesis. In this issue of Cancer Cell, DeNardo and colleagues demonstrate that IL-4-producing T cells enhance metastasis by programming macrophages to produce factors that enhance tumor invasion.

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Year:  2009        PMID： 19647215     DOI： 10.1016/j.ccr.2009.07.007

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  8 in total

1.  Tumor development in murine ulcerative colitis depends on MyD88 signaling of colonic F4/80+CD11b(high)Gr1(low) macrophages.

Authors:  Gabriela Schiechl; Bernhard Bauer; Ivan Fuss; Sven A Lang; Christian Moser; Petra Ruemmele; Stefan Rose-John; Markus F Neurath; Edward K Geissler; Hans-Jürgen Schlitt; Warren Strober; Stefan Fichtner-Feigl
Journal:  J Clin Invest       Date:  2011-04-25       Impact factor: 14.808

2.  Capturing and characterizing immune cells from breast tumor microenvironment: an innovative surgical approach.

Authors:  Mohamed El-Shinawi; Sayed F Abdelwahab; Maha Sobhy; Mohamed A Nouh; Bonnie F Sloane; Mona Mostafa Mohamed
Journal:  Ann Surg Oncol       Date:  2010-03-24       Impact factor: 5.344

3.  JAK2 expression is associated with tumor-infiltrating lymphocytes and improved breast cancer outcomes: implications for evaluating JAK2 inhibitors.

Authors:  Chris P Miller; Jason D Thorpe; Amanda N Kortum; Catherine M Coy; Wei-Yi Cheng; Tai-Hsien Ou Yang; Dimitris Anastassiou; J David Beatty; Nicole D Urban; C Anthony Blau
Journal:  Cancer Immunol Res       Date:  2014-01-15       Impact factor: 11.151

4.  Pretreatment levels of circulating Th1 and Th2 cytokines, and their ratios, are associated with ER-negative and triple negative breast cancers.

Authors:  Chi-Chen Hong; Song Yao; Susan E McCann; Ree Y Dolnick; Paul K Wallace; Zhihong Gong; Lei Quan; Kelvin P Lee; Sharon S Evans; Elizabeth A Repasky; Stephen B Edge; Christine B Ambrosone
Journal:  Breast Cancer Res Treat       Date:  2013-04-30       Impact factor: 4.872

5.  The sympathetic nervous system induces a metastatic switch in primary breast cancer.

Authors:  Erica K Sloan; Saul J Priceman; Benjamin F Cox; Stephanie Yu; Matthew A Pimentel; Veera Tangkanangnukul; Jesusa M G Arevalo; Kouki Morizono; Breanne D W Karanikolas; Lily Wu; Anil K Sood; Steven W Cole
Journal:  Cancer Res       Date:  2010-09-07       Impact factor: 12.701

6.  Increased entropy of signal transduction in the cancer metastasis phenotype.

Authors:  Andrew E Teschendorff; Simone Severini
Journal:  BMC Syst Biol       Date:  2010-07-30

Review 7.  The Eya phosphatase: Its unique role in cancer.

Authors:  Hengbo Zhou; Lingdi Zhang; Rebecca L Vartuli; Heide L Ford; Rui Zhao
Journal:  Int J Biochem Cell Biol       Date:  2017-09-05       Impact factor: 5.085

8.  Improved prognostic classification of breast cancer defined by antagonistic activation patterns of immune response pathway modules.

Authors:  Andrew E Teschendorff; Sergio Gomez; Alex Arenas; Dorraya El-Ashry; Marcus Schmidt; Mathias Gehrmann; Carlos Caldas
Journal:  BMC Cancer       Date:  2010-11-04       Impact factor: 4.430
  8 in total

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