Animal research ethics in Africa: an overview.

With research projects that use animals on the increase worldwide and in Africa in particular, animal research ethics should continue to be reviewed to improve the welfare of animals used in research. The welfare of animals used in research has gained attention globally that has led to the development of guidelines and in some instances national laws governing animal experimentation. Although there may not be empirical data on the existence or adequacy of national and/or institutional policies and guidelines on the use of animals in research in Africa, most African countries are not yet at the same level as developed countries. Consequently, some researchers based at institutions in developed countries may be tempted to 'export' their research activities to collaborating African institutions where ethical and legal frameworks on use of animals may be less stringent than in the developed countries. An appreciation of the intrinsic value of animals should be enough driving force for human beings to strive to promote humane treatment of animals. This paper gives an overview of uses and potential abuses of animals in research for the benefit of stakeholders such as researchers, research institutions, Ethics Review Committees (ERCs) and policy makers and ends with suggestions on possible ways of ensuring humane treatment of animals used in research in Africa in particular and globally in general.