Literature DB >> 19646808

Mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) in carcinogenesis.

Irena Martin-Kleiner1, Koraljka Gall Troselj.   

Abstract

The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. Its tumor suppressor role was recognized a long time ago. However, due to its multifunctionality, it is not easy to understand the extent of its relevance to normal cellular physiology. Accordingly, it is even more difficult understanding its role in carcinogenesis. This review presents critical and focused highlights of data relating to M6P/IGF2R, obtained during more than 25 years of cancer research. Copyright 2009 Elsevier Ireland Ltd. All rights reserved.

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Year:  2009        PMID： 19646808     DOI： 10.1016/j.canlet.2009.06.036

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  28 in total

1.  Dominant-negative effect of truncated mannose 6-phosphate/insulin-like growth factor II receptor species in cancer.

Authors:  Jodi L Kreiling; Michelle A Montgomery; Joseph R Wheeler; Jennifer L Kopanic; Christopher M Connelly; Megan E Zavorka; Jenna L Allison; Richard G Macdonald
Journal:  FEBS J       Date:  2012-07-02       Impact factor: 5.542

Review 2.  Targeting the insulin-like growth factor pathway in hepatocellular carcinoma.

Authors:  Mónica Enguita-Germán; Puri Fortes
Journal:  World J Hepatol       Date:  2014-10-27

3.  The molecular basis of IGF-II/IGF2R recognition: a combined molecular dynamics simulation, free-energy calculation and computational alanine scanning study.

Authors:  Jingjing Guo; Xiaoting Wang; Huijun Sun; Huanxiang Liu; Xiaojun Yao
Journal:  J Mol Model       Date:  2011-07-15       Impact factor: 1.810

4.  Insulin-Like Growth Factor 2 Receptor Expression Is Promoted by Human Herpesvirus 8-Encoded Interleukin-6 and Contributes to Viral Latency and Productive Replication.

Authors:  Qian Li; Daming Chen; Qiwang Xiang; John Nicholas
Journal:  J Virol       Date:  2019-02-19       Impact factor: 5.103

Review 5.  A Historical Review of Brain Drug Delivery.

Authors:  William M Pardridge
Journal:  Pharmaceutics       Date:  2022-06-16       Impact factor: 6.525

6.  Identification and characterization of a membrane receptor that binds to human STC1.

Authors:  Hin Ting Wan; Alice Hm Ng; Wang Ka Lee; Feng Shi; Chris Kong-Chu Wong
Journal:  Life Sci Alliance       Date:  2022-07-07

7.  Insulin-like growth factor 2 (IGF2) expression in adrenocortical disease due to PRKAR1A mutations compared to other benign adrenal tumors.

Authors:  Kiran S Nadella; Annabel Berthon; Madson Q Almeida; Isaac Levy; Fabio R Faucz; Constantine A Stratakis
Journal:  Endocrine       Date:  2021-01-09       Impact factor: 3.633

8.  The association of soluble IGF2R and IGF2R gene polymorphism with type 2 diabetes.

Authors:  Suwannee Chanprasertyothin; Wallaya Jongjaroenprasert; Boonsong Ongphiphadhanakul
Journal:  J Diabetes Res       Date:  2015-04-02       Impact factor: 4.011

9.  Identifying Potential Neoantigens for Cervical Cancer Immunotherapy Using Comprehensive Genomic Variation Profiling of Cervical Intraepithelial Neoplasia and Cervical Cancer.

Authors:  Chaohui Bao; Na An; Hong Xie; Ling Xu; Boping Zhou; Jun Luo; Wanqiu Huang; Jian Huang
Journal:  Front Oncol       Date:  2021-06-17       Impact factor: 6.244

10.  Identification of cell surface proteins as potential immunotherapy targets in 12 pediatric cancers.

Authors:  Rimas J Orentas; James J Yang; Xinyu Wen; Jun S Wei; Crystal L Mackall; Javed Khan
Journal:  Front Oncol       Date:  2012-12-17       Impact factor: 6.244
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