Anita Agrawal1, Jill Nation2, Prafull Ghatage2, Pamela Chu2, Sue Ross3, Anthony Magliocco4. 1. Department of Obstetrics and Gynaecology, Division of Gynaecologic Oncology, University of Calgary, Calgary AB. 2. Department of Obstetrics and Gynaecology, University of Calgary, Calgary AB. 3. Department of Obstetrics and Gynaecology, University of Calgary, Calgary AB; Department of Family Medicine, University of Calgary, Calgary AB; Department of Community Health Sciences, University of Calgary, Calgary AB. 4. Department of Pathology and Laboratory Medicine, University of Calgary, Calgary AB; Tom Baker Cancer Centre, Calgary AB.
Abstract
BACKGROUND: Endometriosis usually affects women in their reproductive years. Most commonly, the pelvic organs are involved. Involvement of the chest wall after hysterectomy is rare. The incidence of malignant transformation is less than 1% for ovarian endometriosis, but is unknown for extraovarian endometriosis. CASE: A 47-year-old woman who had undergone hysterectomy and bilateral salpingo-oophorectomy for endometriosis presented four years after surgery with a well-differentiated endometrioid adenocarcinoma arising in the background of endometriosis in the right chest wall. The tumour was resected, and the patient received six courses of adjuvant chemotherapy. CONCLUSION: Women with endometriosis-associated cancer require individualized management options, depending upon the histopathology and stage of the cancer.
BACKGROUND:Endometriosis usually affects women in their reproductive years. Most commonly, the pelvic organs are involved. Involvement of the chest wall after hysterectomy is rare. The incidence of malignant transformation is less than 1% for ovarian endometriosis, but is unknown for extraovarian endometriosis. CASE: A 47-year-old woman who had undergone hysterectomy and bilateral salpingo-oophorectomy for endometriosis presented four years after surgery with a well-differentiated endometrioid adenocarcinoma arising in the background of endometriosis in the right chest wall. The tumour was resected, and the patient received six courses of adjuvant chemotherapy. CONCLUSION:Women with endometriosis-associated cancer require individualized management options, depending upon the histopathology and stage of the cancer.